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5'-AMP-activated protein kinase subunit gamma-1
go.drugbank.com/bio_entities/BE0009988TargetHumansAMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:21680840, PubMed:24563466). In response to reduction of intracellular ...
Polypeptides: 5'-AMP-activated protein kinase subunit gamma-13-oxo-5-alpha-steroid 4-dehydrogenase 1
go.drugbank.com/bio_entities/BE0000539TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), a more potent androgen as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a key step in male sexual
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 1Synonyms: Steroid 5-alpha-reductase 1High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
go.drugbank.com/bio_entities/BE0000706TargetHumansHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:19350606, PubMed:8389765, PubMed:9195912). May have a role in muscle signal transduction (PubMed:9195912)
Polypeptides: High affinity 3',5'-cyclic-AMP phosphodiesterase 7AFunction: 3',5'-cyclic-AMP phosphodiesterase activityMitogen-activated protein kinase kinase kinase kinase 5
go.drugbank.com/bio_entities/BE0009474TargetHumansMay play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway
Polypeptides: Mitogen-activated protein kinase kinase kinase kinase 5Synonyms: MEKKK 5, MEK kinase kinase 5Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
go.drugbank.com/bio_entities/BE0014411TargetHumansAlso has 3'->5' exonuclease activity towards double-stranded (ds)DNA with a 5'-overhang (PubMed:11863428). … Unwinds some G-quadruplex DNA (d(CGG)n tracts); unwinding seems to occur in both 5'-3' and 3'-5' direction and requires a short single-stranded tail (PubMed:10212265). d(CGG)n tracts have a propensity
Polypeptides: Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNFunction: 3'-5' DNA helicase activityProcainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Synonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesCY-1503
go.drugbank.com/drugs/DB17605InvestigationalCY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl
Synonyms: CY 1503Ferrimannitol ovalbumin
go.drugbank.com/drugs/DB15824InvestigationalFerrimannitol-ovalbumin (FMOA) is an adduct between ovalbumin and the complex Fe(III)-mannitol.
Products: GRANULOFER 40 MG SAŞE, 30 ADETFluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnFluticasone is a synthetic glucocorticoid available as 2 esters, [DB08906] and [DB00588][F4355,F4358,F4361,F4364][FDA Label].
Mixtures: PAVTIDE DISKUS 100 MCG INHALASYON ICIN TOZ, 60 DOZ, SERETIDE 100 MCG DISKUS INHALASYON İÇİN TOZ, 60 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersGadoxetic acid
go.drugbank.com/drugs/DB08884ApprovedInvestigationalEthoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. … Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.
Categories: Compounds used in a research, industrial, or household settingProducts: PRIMOVIST 0,25 MMOL/ML ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET, Primovist 0.25 mmol/ml Solution for injection