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Displaying results 3861 - 3870 of 10000 in total
  1. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0008383
    TargetStaphylococcus aureus

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  2. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000429
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  3. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000798
    TargetEscherichia coli (strain K12)

    MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  4. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0003726
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A
  5. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    In the nervous system, also plays a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. … In addition to its role in axonal guidance plays a role in synaptic plasticity.

    Polypeptides: Ephrin type-A receptor 4
  6. Drug

    Calmangafodipir

    go.drugbank.com/drugs/DB18398
    Investigational

    Synonyms: Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine) manganese complexes trisodium trihydrogen manganate, Calmangafodipir (ca4mn(dpdp)5)Categories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  7. Drug

    Phenaglycodol

    go.drugbank.com/drugs/DB19373
    Experimental

    Synonyms: 2,3-butanediol, 2-(4-chlorophenyl)-3-methyl-, (+/-)-2-(p-chlorophenyl)-3-methyl-2,3-butanediol
  8. Drug

    Fosigotifator

    go.drugbank.com/drugs/DB19409
    Investigational

    Fosigotifator is under investigation in clinical trial NCT05757141 (An Open-label Exploratory Study of ABBV-CLS-7262 Subjects With Vanishing White Matter Disease).

    Synonyms: Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate - 2-amino-2- (hydroxymethyl)propane-1,3-diol (1/1/1)
  9. Drug

    EB05

    go.drugbank.com/drugs/DB16477
    Investigational

    EB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.

    Synonyms: Immunoglobulin G1 [326-serine,329-phenylalanine,de-448-lysine], anti-(human Toll-like receptor 4) (human-Mus musculus monoclonal EB05 γ1-chain), disulfide with human-Mus musculus monoclonal EB05 κ-chain
  10. Drug

    Fluorofuranylnorprogesterone F-18

    go.drugbank.com/drugs/DB15282
    Investigational

    Fluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).

    Synonyms: 19-NORPREGN-4-ENE-3,20-DIONE, 21-(FLUORO-18F)-16,17-((R)-(2-FURANYLMETHYLENE)BIS(OXY))-, (16.ALPHA.)-, FFNP F-18