Search

Displaying results 3891 - 3900 of 10000 in total
  1. Target

    Excitatory amino acid transporter 3

    go.drugbank.com/bio_entities/BE0001054
    TargetTransporterHumans

    Can also transport L-cysteine (PubMed:21123949). … Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949).

    Synonyms: Neuronal and epithelial glutamate transporter
  2. Target

    Ribosomal protein S6 kinase alpha-4

    go.drugbank.com/bio_entities/BE0004614
    TargetHumans

    Plays an essential role in the control of RELA transcriptional activity in response to TNF. … Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

    Synonyms: Nuclear mitogen- and stress-activated protein kinase 2
  3. Target

    Zinc transporter ZIP12

    go.drugbank.com/bio_entities/BE0009897
    TransporterHumans

    May play a role in neurulation and neurite extension. … May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis

    Synonyms: Zrt- and Irt-like protein 12
  4. Target

    Zinc transporter ZIP13

    go.drugbank.com/bio_entities/BE0009900
    TransporterHumans

    Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol (PubMed:21917916, PubMed:23213233).

    Synonyms: Zrt- and Irt-like protein 13
  5. Drug

    Ensitrelvir

    go.drugbank.com/drugs/DB18834
    ApprovedInvestigational

    Ensitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).

  6. Drug

    Temafloxacin

    go.drugbank.com/drugs/DB01405
    ApprovedWithdrawn

    It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three … Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class.

    Categories: Topoisomerase II Inhibitors
  7. Drug

    Udenafil

    go.drugbank.com/drugs/DB06267
    Approved

    Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. … It is not yet approved for use in the U.S., E.U., or Canada.

    Categories: Drugs Used in Erectile Dysfunction, Genito Urinary System and Sex HormonesProducts: ZYDENA 200MG
  8. Drug

    Selenomethionine

    go.drugbank.com/drugs/DB11142
    ApprovedInvestigational

    Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. … *In vivo*, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important

    Categories: Amino Acids, Peptides, and Proteins
  9. Drug

    Sodium phosphate, monobasic, unspecified form

    go.drugbank.com/drugs/DB14503
    Approved

    Mixtures: Up and Up Ready To Use Enema, Pure and Gentle Laxative
  10. Drug

    Black cohosh

    go.drugbank.com/drugs/DB13975
    Approved

    in treating the symptoms of sleep and mood disturbance, and hot flushes. … [A32543] The American College of Obstetrics and Gynecology guidelines on the use of botanicals, such as black cohosh, for the management of menopausal symptoms the use of for up to six months, especially

    Categories: Herbs and Natural Products, Genito Urinary System and Sex Hormones