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Azimilide
go.drugbank.com/drugs/DB04957InvestigationalIt is not approved for use in any country, but is currently in clinical trials in the United States. … Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels.
Synonyms: 1-((5-(P-CHLOROPHENYL)FURFURYLIDENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)HYDANTOIN, 2,4-IMIDAZOLIDINEDIONE, 1-(((5-(4-CHLOROPHENYL)-2-FURANYL)METHYLENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)-Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingDiosmin
go.drugbank.com/drugs/DB08995ApprovedInvestigationalChronic venous insufficiency is a common condition the western population. … Diosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile.[A232890,T840,L33040]
Synonyms: 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside, 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinosideMixtures: VENADOL® F, VEDIPAL ® 1000Umifenovir
go.drugbank.com/drugs/DB13609Investigational[A191475] It has been in use in Russia for approximately 25 years and in China since 2006. … [A191475] Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Synonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterMixtures: L-OMBRIX-DUET, L-OMBRIX-DUETPoloxamer 407
go.drugbank.com/drugs/DB11252InvestigationalIt consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. … Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant.
Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsProducts: K-MOM Baby ToothCholine magnesium trisalicylate
go.drugbank.com/drugs/DB01401ApprovedCholine magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug.
Categories: Non COX-2 selective NSAIDSSorbitan monooleate
go.drugbank.com/drugs/DB19493ExperimentalSorbitan monooleate is a small molecule drug. Sorbitan monooleate has a monoisotopic molecular weight of 428.31 Da.
Synonyms: Sorbitan, mono-9-octadecenoateCategories: Compounds used in a research, industrial, or household settingChlormerodrin
go.drugbank.com/drugs/DB00534ApprovedWithdrawnChlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. … It is no longer used and has been replaced with new classes of diuretic drugs.
Synonyms: 1-[3-(chloromercuri)-2-methoxypropyl]urea, {3-[(aminocarbonyl)amino]-2-methoxypropyl}chloromercurySinapultide
go.drugbank.com/drugs/DB11332ApprovedWithdrawn[L2505] Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in preterm infants. … Surfactant replacement therapy has been commonly used to prevent and treat RDS in these newborns and is now a standard of care.
Agmatine
go.drugbank.com/drugs/DB08838ExperimentalAs an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the … Agmantine is a natural metabolite of the amino acid arginine.
Synonyms: N-(4-aminobutyl)guanidine, 1-amino-4-guanidobutaneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates