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Felcisetrag
go.drugbank.com/drugs/DB12725InvestigationalFelcisetrag (TD-8954) has been used in trials studying the treatment of Enteral Feeding Intolerance and Gastrointestinal Motility Disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds, 1-RingMephenesin
go.drugbank.com/drugs/DB13583ApprovedWithdrawnMephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression [A32760]. It first entered use in the 1950s.
Synonyms: 3-(O-METHYLPHENOXY)-1,2-PROPANEDIOLAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalThis recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2.
Synonyms: 125-L-Serine-2-133-interleukin 2, 125-L-serine-2-133-interleukin 2 (human reduced)Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsTesamorelin
go.drugbank.com/drugs/DB08869ApprovedInvestigationalTesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Synonyms: N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet), GHRH(1-44)Products: Egrifta SvEpithelial sodium channel subunit alpha
go.drugbank.com/bio_entities/BE0000190TargetTransporterHumansThis is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis (PubMed:30251954, PubMed:32729833, PubMed:8023962, PubMed:8278374, PubMed...
Synonyms: Alpha-NaCHTurpentine
go.drugbank.com/drugs/DB11120ApprovedTurpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene with lesser amounts of carene, camphene, dipentene, and terpinolene. … It is used as a solvent and base material in organic synthesis reactions.
Mixtures: NORAVER U, BUĞUMENTOL BUĞU, 40 GCategories: Compounds used in a research, industrial, or household settingPromestriene
go.drugbank.com/drugs/DB12487InvestigationalPromestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. … The concern with absorbed vaginal estrogens or estrogen analogs is that they activate occult sites of residual breast cancer or negate the tumor suppressive effects of aromatase inhibitor adjuvant therapy
Categories: Sex Hormones and Modulators of the Genital SystemProducts: ANTROFI®, COLPOTROFINE® CAPSULAS VAGINALESCefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnCefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum.
Categories: Heterocyclic Compounds, 2-RingInternational brands: Cefthan-DSProxibarbal
go.drugbank.com/drugs/DB13253ApprovedProxibarbal is a derivative of barbiturates, which has been used to treat migraines. … Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic thrombocytopenia [L5476].
Categories: Heterocyclic Compounds, 1-RingCyclopentolate
go.drugbank.com/drugs/DB00979ApprovedA parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Mixtures: Mydriatic-3Synonyms: 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate, 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester