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Zolpidem Action Pathway (New)
smpdb.ca/view/SMP0125072Drug actionZolpidem is a sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Zolpidem binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-gated chloride channel in different sites of the ce...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Chlordiazepoxide Action Pathway
smpdb.ca/view/SMP0126120Drug actionChlordiazepoxide is a benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) b...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Chlordiazepoxide · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Sevoflurane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126170Drug actionSevoflurane is an inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures. It can be found under the brand names Sevorane, Sojourn, and Ultane. It is a volatile, non-flammable comp...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Clobazam Action Pathway
smpdb.ca/view/SMP0126121Drug actionClobazam is a benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. It can be found under the brand names Onfi and Sympazan. Clobazam acts on the GABAA receptor to increase GABAnergic transmission,...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Pentobarbital Action Pathway
smpdb.ca/view/SMP0126165Drug actionPentobarbital is a barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually gi...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Pentobarbital · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Amobarbital Action Pathway
smpdb.ca/view/SMP0126834Drug actionAmobarbital, a derivative of barbiturate, finds application in inducing sedation during medical procedures, short-term management of insomnia, and acute control of refractory tonic-clonic seizures. As a barbiturate possessing hypnotic an...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Butalbital Action Pathway
smpdb.ca/view/SMP0126149Drug actionButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … Typically indicated to manage tension (or muscle contraction) headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid, acetaminophen, aspirin, and caffeine
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Halothane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126161Drug actionHalothane is a general inhalation anesthetic used for the induction and maintenance of general anesthesia. A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analges...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Thiopental Action Pathway
smpdb.ca/view/SMP0126813Drug actionThiopental is a barbiturate utilized for inducing general anesthesia, managing convulsions, and reducing intracranial pressure. Administered intravenously, this barbiturate is employed to induce general anesthesia promptly, achieve tempo...
Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2Secobarbital Action Pathway
smpdb.ca/view/SMP0126809Drug actionSecobarbital is a barbiturate derivative that serves as a short-term treatment for insomnia, offering an array of properties including anesthesia induction, anticonvulsant effects, and sedative-hypnotic capabilities. It finds use in indu...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Secobarbital · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2