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Izalontamab brengitecan
go.drugbank.com/drugs/DB22567InvestigationalIzalontamab brengitecan is under investigation in clinical trial NCT07054567 (A Study of BL-B01D1 + Pembrolizumab ± Bevacizumab in Patients With Recurrent or Metastatic Cervical Cancer and Endometrial
Fruquintinib
go.drugbank.com/drugs/DB11679ApprovedInvestigationalThe first approach can be exemplified by [bevacizumab], a VEGF-A trap antibody. … Although [bevacizumab] is successful in sustaining target inhibition, mandatory intravenous dosing, immunogenicity, and the potential to induce autoimmune diseases hinder its clinical application.
Unresectable Hepatocellular Carcinoma (HCC)
go.drugbank.com/conditions/DBCOND0083730Apomab
go.drugbank.com/drugs/DB15022InvestigationalApomab is under investigation in clinical trial NCT00851136 (A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced
Metastatic Non-squamous Non Small Cell Lung Cancer
go.drugbank.com/conditions/DBCOND0044105Metastatic Renal Cell Carcinoma ( mRCC)
go.drugbank.com/conditions/DBCOND0123126Neovascular (Wet) Age-related Macular Degeneration (nAMD)
go.drugbank.com/conditions/DBCOND0158368Tipiracil
go.drugbank.com/drugs/DB09343ApprovedInvestigationalTipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its ...
Parsatuzumab
go.drugbank.com/drugs/DB14897InvestigationalParsatuzumab is under investigation in clinical trial NCT01366131 (Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced
SS1(dsFv)-PE38
go.drugbank.com/drugs/DB17579InvestigationalSS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma