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Displaying results 31 - 40 of 251 in total
  1. Target

    Cyclic nucleotide-gated potassium channel mll3241

    go.drugbank.com/bio_entities/BE0002795
    TargetRhizobium loti (strain MAFF303099)

    Cyclic nucleotide-regulated potassium channel activated by cAMP.

    Polypeptides: Cyclic nucleotide-gated potassium channel mll3241
  2. Target

    Potassium channel subfamily K member 9

    go.drugbank.com/bio_entities/BE0003583
    TargetHumans

    Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties (By similarity) (PubMed:23169818, PubMed:38630723). … mechanism that controls arterial blood pressure and electrolyte homeostasis (By similarity)

    Polypeptides: Potassium channel subfamily K member 9Synonyms: Two pore potassium channel KT3.2, Acid-sensitive potassium channel protein TASK-3
  3. Target

    Mitochondrial potassium channel ATP-binding subunit

    go.drugbank.com/bio_entities/BE0003673
    TransporterHumans

    ATP-binding subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)) (PubMed:31435016). … Together with pore-forming subunit CCDC51/MITOK of the mitoK(ATP) channel, mediates ATP-dependent potassium currents across the mitochondrial inner membrane (PubMed:31435016).

    Polypeptides: Mitochondrial potassium channel ATP-binding subunit
  4. Target

    Potassium channel subfamily K member 10

    go.drugbank.com/bio_entities/BE0013513
    TargetHumans

    Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties (PubMed:30573346). … Permeable to other monovalent ions such as Rb(+) and Cs(+) (PubMed:26919430)

    Polypeptides: Potassium channel subfamily K member 10Synonyms: Outward rectifying potassium channel protein TREK-2
  5. Target

    Voltage-gated inwardly rectifying potassium channel KCNH6

    go.drugbank.com/bio_entities/BE0000462
    TargetHumans

    Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. … during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization.

    Polypeptides: Voltage-gated inwardly rectifying potassium channel KCNH6Synonyms: Ether-a-go-go-related gene potassium channel 2, Voltage-gated potassium channel subunit Kv11.2
  6. Target

    Calcium-activated potassium channel subunit beta-2

    go.drugbank.com/bio_entities/BE0003196
    TargetHumans

    Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. … Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex.

    Polypeptides: Calcium-activated potassium channel subunit beta-2Synonyms: Calcium-activated potassium channel, subfamily M subunit beta-2
  7. Target

    Calcium-activated potassium channel subunit beta-4

    go.drugbank.com/bio_entities/BE0004424
    TargetHumans

    Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. … Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics.

    Polypeptides: Calcium-activated potassium channel subunit beta-4Synonyms: Calcium-activated potassium channel, subfamily M subunit beta-4
  8. Target

    Sodium/potassium-transporting ATPase subunit beta-2

    go.drugbank.com/bio_entities/BE0005018
    TransporterTargetHumans

    This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

    Polypeptides: Sodium/potassium-transporting ATPase subunit beta-2Synonyms: Sodium/potassium-dependent ATPase subunit beta-2
  9. Target

    Voltage-gated delayed rectifier potassium channel KCNH1

    go.drugbank.com/bio_entities/BE0005191
    TargetHumans

    Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not … Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PubMed:23881642)

    Polypeptides: Voltage-gated delayed rectifier potassium channel KCNH1Synonyms: Ether-a-go-go potassium channel 1, Voltage-gated potassium channel subunit Kv10.1
  10. Target

    Voltage-gated inwardly rectifying potassium channel KCNH2

    go.drugbank.com/bio_entities/BE0000090
    TargetTransporterHumans

    Forms a stable complex with KCNE1 or KCNE2, and that this heteromultimerization regulates inward rectifier potassium channel activity (PubMed:10219239, PubMed:9230439) … Channel properties are modulated by cAMP and subunit assembly (PubMed:10837251).

    Polypeptides: Voltage-gated inwardly rectifying potassium channel KCNH2Synonyms: Ether-a-go-go-related gene potassium channel 1, Voltage-gated potassium channel subunit Kv11.1