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Displaying results 31 - 40 of 1567 in total
  1. Pathway

    Hydroflumethiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123142
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. … transporter which transports chloride into the interstitium-blood.

    Drugs: Hydroflumethiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  2. Pathway

    Chlorthalidone Diuretic Action Pathway

    smpdb.ca/view/SMP0123149
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Chlorthalidone · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  3. Pathway

    Polythiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123144
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Polythiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  4. Pathway

    Cyclothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123145
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. … transporter which transports chloride into the interstitium-blood.

    Drugs: Cyclothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  5. Pathway

    Benzthiazide Action Pathway

    smpdb.ca/view/SMP0126366
    Drug action

    In consequence, this will increase potassium excretion via the sodium-potassium exchange mechanism. The exact name of the inhibited transporter is the solute carrier family 12 member 3. … This inhibition of the cotransporter results in the increased excretion of sodium, chloride, and, in consequence, water.

    Drugs: Benzthiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  6. Pathway

    Bumetanide Diruretic Action Pathway

    smpdb.ca/view/SMP0124517
    Drug action

    Bumetanide is a loop diuretic drug, administered orally or intravenously the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome. It targets the nephrons of the kidney, ...

    Drugs: Bumetanide · Potassium cation
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  7. Pathway

    Amiloride Action Pathway (New)

    smpdb.ca/view/SMP0126243
    Drug action

    Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. … This promotes the loss of sodium and water from the body, but without depleting potassium.

    Drugs: Amiloride · Potassium cation · Urea
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  8. Pathway

    Bendroflumethiazide Action Pathway (New)

    smpdb.ca/view/SMP0123062
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride, and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Bendroflumethiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  9. Pathway

    Chlorothiazide Action Pathway

    smpdb.ca/view/SMP0123141
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occurs. … transporter which transports chloride into the interstitium-blood.

    Drugs: Chlorothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1
  10. Pathway

    Methyclothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0123143
    Drug action

    In the distal convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. … transporter which transports chloride into the interstitium-blood.

    Drugs: Methyclothiazide · Potassium cation · Calcium
    Enzymes: Chloride channel protein ClC-Ka, Sodium/potassium-transporting ATPase subunit alpha-1