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Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein.
Categories: Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 500®IU / VIAL, ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium _Streptomyces lincolnensis_ in Lincoln, Nebraska. … ] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in
Products: LINCOCIN 600 MG IM/IV AMPUL, 1 ADETPancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Mixtures: Alka-pan TabletsProducts: KREON 8000 IU KAPSUL, 20 ADET, KREON 10000 IU KAPSUL, 100 ADETCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigationalCarboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Categories: Compounds used in a research, industrial, or household settingSynonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)Azithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIt is structurally related to erythromycin [A174169]. … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
Products: ZITHROMAX IV, Azithromycin for Injection USPAlfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalIt produces an early peak analgesic effect and fast recovery of consciousness. … Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Products: Alfentanil Injection USPAmyl Nitrite
go.drugbank.com/drugs/DB01612ApprovedAs an inhalant, it also has psychoactive effect which has led to illegal drug use. … Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning.
Products: AMYL NITRITE INHALANT USP 0.3 ml/ampouleHydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure. … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.
Products: Novo-hylazin Tab 10mg USP, Hydralazine Hydrochloride Injection, USPFolic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … Inadequate folate levels can result in a number of health concerns including cardiovascular disease, megaloblastic anemias, cognitive deficiencies, and neural tube defects (NTDs).
Mixtures: Re Kar C Plus, Stress Formula Multivitamin Tablets USPProducts: Folic Acid Inj 5mg/ml USP, Folic Acid Tab 0.4mg USPErenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalIt is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass, each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label … CGRP receptor, which is believed to play a critical role in migraine [L2823].
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsProducts: AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML, AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/ML