Search
Rufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. … Clinical trials suggest its efficacy in the treatment of partial seizures.
Categories: Cytochrome P-450 CYP3A Inducers, Heterocyclic Compounds, 1-RingProducts: INOVELON® 400 MG, INOVELON FILM-COATED TABLET 200 MGTrastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: T-DM1Ribose-5-phosphate Isomerase Deficiency
smpdb.ca/view/SMP0000519DiseaseIt reversibly converts D-ribulose 5-phosphate into D-ribose 5-phosphate. … Ribose-5-phosphate isomerase (RPI) deficiency, is a genetic disorder caused by mutations in the RPIA gene that codes for RPI.
Drugs: Adenosine phosphate · ATP · Magnesium cation · Iron · 5-O-phosphono-alpha-D-ribofuranosyl diphosphate · D-glyceraldehyde 3-phosphate +4 moreEnzymes: Ribose-5-phosphate isomeraseAcylcarnitine 2-Hydroxy-5-octenoylcarnitine
smpdb.ca/view/SMP0123373Metabolic2-Hydroxy-5-octenoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 2-hydroxy-5-octenoyl-CoA reacts with L-carnitine to form 2-hydroxy-5-octenoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 6-hydroxynon-5-enoylcarnitine
smpdb.ca/view/SMP0123424Metabolic6-hydroxynon-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 6-hydroxynon-5-enoyl-CoA reacts with L-carnitine to form 6-hydroxynon-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 5-Hydroxydec-3-enoylcarnitine
smpdb.ca/view/SMP0123867Metabolic5-Hydroxydec-3-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-3-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-3-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 5-Hydroxydec-6-enoylcarnitine
smpdb.ca/view/SMP0123870Metabolic5-Hydroxydec-6-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-6-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-6-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 2-Hydroxyundec-5-enoylcarnitine
smpdb.ca/view/SMP0123960Metabolic2-Hydroxyundec-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 2-hydroxyundec-5-enoyl-CoA reacts with L-carnitine to form 2-hydroxyundec-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 10-Hydroxydodec-5-enedioylcarnitine
smpdb.ca/view/SMP0124031Metabolic10-Hydroxydodec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxydodec-5-enedioyl-CoA reacts with L-carnitine to form 10-hydroxydodec-5-enedioylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 5-Hydroxydodeca-7,9-dienoylcarnitine
smpdb.ca/view/SMP0124040Metabolic5-Hydroxydodeca-7,9-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydodeca-7,9-dienoyl-CoA reacts with L-carnitine to form 5-hydroxydodeca-7,9-dienoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5