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Displaying results 4041 - 4050 of 10000 in total
  1. Target

    Pepsin A

    go.drugbank.com/bio_entities/BE0004062
    TargetSIV-mac

    Polypeptides: Pepsin A
  2. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Estradiol is a naturally occurring hormone circulating endogenously in females. … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.

    Synonyms: 17-β estradiolInternational brands: Estraderm MX
  3. Drug

    IDN-7314

    go.drugbank.com/drugs/DB18073
    Experimental

    Synonyms: (s)-3-((s)-2-(2-((2,6-difluorophenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid, L-alaninamide, n-(2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl)-
  4. Target

    Arylsulfatase A

    go.drugbank.com/bio_entities/BE0003195
    TargetEnzymeHumans

    Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein … Also involved in the catabolism of other sulfoglycosphingolipids such as SB1a and SM3 (beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) (By similarity)

    Polypeptides: Arylsulfatase A
  5. Target

    Bontoxilysin-A

    go.drugbank.com/bio_entities/BE0004102
    TargetClostridium botulinum

    Polypeptides: Bontoxilysin-ASynonyms: A, boNT/A
  6. Target

    Filamin-A

    go.drugbank.com/bio_entities/BE0009099
    TargetHumans

    Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.

    Polypeptides: Filamin-ASynonyms: FLN-A
  7. Target

    Toxin A

    go.drugbank.com/bio_entities/BE0010938
    TargetPeptoclostridium difficile

    Toxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains

    Polypeptides: Toxin A
  8. Indication

    Severe Hemophilia A

    go.drugbank.com/conditions/DBCOND0034640
    Drugs: Valoctocogene roxaparvovec
    Synonyms: Hemophilia A, Severe, Severe Hemophilia A
  9. Drug

    Atomoxetine

    go.drugbank.com/drugs/DB00289
    ApprovedInvestigational

    Long-acting formulations of psychostimulants (such as [DB00422], [DB01576], and [DB01255]) are typically considered the most effective and first-line treatment for ADHD in adults and children as recommended … (NMDA) receptor,[A18263] indicating a role for the glutamatergic system in the pathophysiology of ADHD.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: STRATTERA 4 MG/ML ORAL ÇÖZELTI, ATTEX 4 MG/ML ORAL ÇÖZELTİ, 100 ML
  10. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Mixtures: TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 30 ADET, TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 90 ADETCategories: Compounds used in a research, industrial, or household setting, Vitamin B Complex