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SPC2968
go.drugbank.com/drugs/DB06351InvestigationalSPC2968 is a synthetic antisense oligodeoxynucleotide targeting hypoxia-inducible factor-1alpha (HIF-1alpha). It was under investigation in clinical trial NCT02564614 (A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic ...
Curcuma aromatica root oil
go.drugbank.com/drugs/DB11301ApprovedCurcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called wild tumeric, via steamed distillation. *Curcuma aromatica* belongs to the family Zingiberaceae.
Cataract development
go.drugbank.com/conditions/DBCOND0096028Synonyms: Cataract form (observable entity)Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnIn November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Inecalcitol
go.drugbank.com/drugs/DB04796InvestigationalSynonyms: (7E)-19-Nor-9,10-seco-14beta-cholesta-5,7-dien-23-yne-1alpha,3beta,25-triolDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Categories: Drugs for Functional Gastrointestinal DisordersCobamamide
go.drugbank.com/drugs/DB11191ApprovedNutraceuticalVitamin B12 is a collective term for these variously substituted corrinoids. … Please refer to the entry [DB00115] for more information on this entry.
Categories: Heterocyclic Compounds with 4 or More RingsNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAdimrSC-2f
go.drugbank.com/drugs/DB16436InvestigationalThe AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553].
Oteracil
go.drugbank.com/drugs/DB03209ApprovedInvestigationalfor continued cancer growth. … It functions by blocking the enzyme orotate phosphoribosyltransferase (OPRT), which is involved in the production of 5-FU.