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Desoxycorticosterone pivalate
go.drugbank.com/drugs/DB01134ExperimentalVet approvedFederal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. … Desoxycorticosterone pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. It is white, odorless, and stable in air.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesInternational brands: Cortexone M, Percorten MFilanesib
go.drugbank.com/drugs/DB06040InvestigationalFilanesib is a potent Kinesin Spindle Protein (KSP) inhibitor that caused marked tumor regression in preclinical models of human solid tumors and human leukemias, often leading to durable responses.
Categories: Heterocyclic Compounds, 1-RingMorniflumate
go.drugbank.com/drugs/DB09285InvestigationalMorniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid [L1496].
Categories: Heterocyclic Compounds, 1-RingIrofulven
go.drugbank.com/drugs/DB05786InvestigationalA novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track … Phase III clinical trials involving the drug have been underway since early 2001 at sites in the U.S. and Europe.
Synonyms: 6-hydroxymethylacylfulveneOrmeloxifene
go.drugbank.com/drugs/DB13310ExperimentalOrmeloxifene is a third-generation selective estrogen receptor (ER) modulator. … In India, ormeloxifene has been marketed since the 1990s as a non-hormonal, non-steroidal oral contraceptive taken once a week,[A251450] and it was later introduced for the treatment of dysfunctional uterine
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPZM21
go.drugbank.com/drugs/DB14030ExperimentalPZM21 is a novel μ-opioid receptor (MOPr) ligand that has been reported to induce minimal arrestin recruitment and be devoid of the respiratory depressant effects characteristic of classical μ-opioid ligands
Xylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe effects of xylitol on dental caries have been widely studied, and xylitol is added to some chewing gums and other oral care products to prevent tooth decay and dry mouth. … The recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081].
Synonyms: D-XylitolMixtures: Fluor-a-day, Fluor-a-dayGaradacimab
go.drugbank.com/drugs/DB15629Approved[L53283,A273998] Garadacimab received its first approval in Australia and the UK in January 2025, and has since been approved in a number of other jurisdictions, including the EU and Japan. … Garadacimab is a fully human monoclonal antibody targeted against activated factor XII.
Retifanlimab
go.drugbank.com/drugs/DB15766ApprovedInvestigationalRetifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed … [L45603,L45613] The use of retifanlimab in combination with other oncology drugs for the treatment of metastatic gastroesophageal adenocarcinoma has also been evaluated.[A258383,A258388]
Synonyms: Anti-PD-1 monoclonal antibody MGA012Categories: Programmed Death Receptor-1 Blocking Antibody, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigational[A7624] In the time since its initial approval, pembrolizumab has been granted approval in the treatment of a wide variety of cancers. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Categories: Programmed Death Receptor-1 Blocking Antibody, Programmed Death Receptor-1-directed Antibody InteractionsProducts: KEYTRUDA® 100 MG, KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADET