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Oglufanide
go.drugbank.com/drugs/DB05779InvestigationalOglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. … Oglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection.
Categories: Compounds used in a research, industrial, or household settingSynonyms: L-Glu-L-Trp, L-α-Glu-L-TrpChorionic Gonadotropin (Human)
go.drugbank.com/drugs/DB09126ApprovedInvestigationalVet approvedThis allows the corpus luteum to continuously secrete the hormone progesterone during the first trimester, which is required for maintenance of the uterus and prevents menstruation. … HCG is composed of an alpha and a beta sub-unit.
Products: Powder and Solvent for Solution for Injection, Choriomon 5000 IU powder and solvent for solution for injectionLP-2307
go.drugbank.com/drugs/DB17470ExperimentalLP-2307 is an investigational allogeneic large multivalent immunogen (LMI) vaccine developed by Avanir. It was investigated for melanoma.
Synonyms: LP 2307Zuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigational[A260791] Zuranolone was approved by the FDA on August 4th, 2023, and it is currently the only approved treatment for women with postpartum depression. … Zuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABA<sub>A</sub> receptors.
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive ModulatorSB-509
go.drugbank.com/drugs/DB05579InvestigationalSB-509 is under investigation in multiple clinical trials for the treatment of Diabetic Neuropathy.
CCR5 mAb
go.drugbank.com/drugs/DB05906ExperimentalCCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (
REC-994
go.drugbank.com/drugs/DB15616InvestigationalREC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Lobeglitazone
go.drugbank.com/drugs/DB09198InvestigationalUnlike [DB01132], which is a dual PPAR agonist at PPAR-alpha and PPAR-gamma, Lobeglitazone is a pure PPAR-alpha agonist. … Lobeglitazone is not approved for use by either the Food and Drug Administration (USA), Health Canada, or by the European Medicines Agency for use in the management of diabetes.
Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalIt has little or no analgesic activity. … When diphenoxylate is used alone, it is classified as a Schedule II.
Mixtures: PHARMANIAGA DIPHENOXYLATE A TABLETDicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigationalDicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder … [A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable.
Categories: Drugs for Functional Gastrointestinal Disorders