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Bimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigational[L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin.
Synonyms: (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamideMixtures: BimatoTim-Vision sine 0,3 mg/ml + 5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase
go.drugbank.com/bio_entities/BE0003969TargetBurkholderia xenovorans (strain LB400)Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD).
Polypeptides: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolaseSynonyms: 2,6-dioxo-6-phenylhexa-3-enoate hydrolasePovidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalThis unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
Synonyms: PVP-IMixtures: P-Care MG, Pro-C-Dure 4 KitRepaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalApproximately 90% of a single orally administered dose is eliminated in feces and 8% in urine. … Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight.
Mixtures: PAREGLIN 1 MG/500 MG FILM KAPLI TABLET, 90 ADET, PAREGLIN 2 MG/500 MG FILM KAPLI TABLET, 90 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigationalKetoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. … [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption.
International brands: Orifungal MMixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MG, Ketoconazole 2% / Niacinamide 4%Phenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Synonyms: (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcohol, l-(3-Hydroxyphenyl)-N-methylethanolamineMixtures: L M 6, KONGEST FORTE 650 MG/4 MG/10 MG TABLET, 20 ADETSimethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigational[A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308] … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.
Mixtures: LIBERTRIM® SII 100 MG, Libertrim SIICategories: Compounds used in a research, industrial, or household settingTafluprost
go.drugbank.com/drugs/DB08819ApprovedChemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: TAFLOTAN SINE 15UG/ML, SAFLUTAN®Aluminum oxide
go.drugbank.com/drugs/DB11342ApprovedWithdrawnAluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. … It is considered an indirect additive used in food contact substances by the FDA.
Mixtures: POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSProducts: ALUTACID ANTACID MIXTURE 4% w/w, ALUMINIUM HYDROXIDE MIXTURE BP 4% w/wVLA-4 (very late antigen-4)
go.drugbank.com/bio_entities/BE0010014TargetHumansIntegrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-4/beta-1 is a receptor for VCAM1. … Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin.
Polypeptides: Integrin alpha-4Synonyms: VLA-4 subunit alpha, VLA-4 subunit beta