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Choline magnesium trisalicylate
go.drugbank.com/drugs/DB01401ApprovedTrisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654]. … Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug.
Categories: Non COX-2 selective NSAIDSEnmetazobactam
go.drugbank.com/drugs/DB18716ApprovedInvestigational[A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections. … [A263266] Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-3-yl)methyl)-1-methyl-, inner saltSelenic acid
go.drugbank.com/drugs/DB11068ApprovedIt may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health. … Selenic acid is an organic compound with the chemical formula H2SeO4.
Mixtures: Beta A With Vitamins C and E Plus Selenium, One-A-day Advance Men'sCategories: Compounds used in a research, industrial, or household settingIfenprodil
go.drugbank.com/drugs/DB08954ApprovedInvestigationalWithdrawnBinding at the LBD of the agonists glycine (or D-serine) to the GluN1 subunits and of glutamate to the GluN2 subunits is a regulatory mechanism for channel activation. … [A220118, A220128] One such allosteric regulator is ifenprodil, which was first shown to bind the NMDARs in the 1990s, and specifically to those NMDARs containing the GluN2B subunit.
Categories: Heterocyclic Compounds, 1-RingRomiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalRomiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. … Each subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl.
Products: g/vial, NPLATE® 250 MCGOrmeloxifene
go.drugbank.com/drugs/DB13310Experimental[A251450,A251460] Ormeloxifene is marketed in India as a racemic mixture of the l- (levormeloxifene) and d-isomers (d-ormeloxifene) of _trans_-ormeloxifene. … In India, ormeloxifene has been marketed since the 1990s as a non-hormonal, non-steroidal oral contraceptive taken once a week,[A251450] and it was later introduced for the treatment of dysfunctional uterine
Categories: Sex Hormones and Modulators of the Genital System, Heterocyclic Compounds, 1-RingMelperone
go.drugbank.com/drugs/DB09224InvestigationalMelperone has been used for a span of greater than 30 years in the European Union [L1316]. … It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalAccording to the European Union Cosmetics Regulation (EC) n.1223/2009, phenoxyethanol is authorized as a preservative in cosmetic formulations at a maximum concentration of 1.0% [L2625]. … Phenoxyethanol (EU), or PE, is the most commonly used globally-approved preservative in personal care formulations. It is very easy to use in various types of formulations and is chemically stable.
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, HydroGold 9Synonyms: 1-Hydroxy-2-phenoxyethane, 2-phenoxyethanolDL-dimyristoylphosphatidylcholine
go.drugbank.com/drugs/DB11283ApprovedA synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection [A32711]
Categories: Compounds used in a research, industrial, or household settingSynonyms: l-α-dimyristoylphosphatidylcholineNorepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalNorepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter.
Mixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUSCategories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor Agonists