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Sodium channel protein type 5 subunit alpha
go.drugbank.com/bio_entities/BE0000197TargetHumansPore-forming subunit of Nav1.5, a voltage-gated sodium (Nav) channel that directly mediates the depolarizing phase of action potentials in excitable membranes (PubMed:33712541, PubMed:40768348). Navs, also called VGSCs (voltage-gated sod...
Polypeptides: Sodium channel protein type 5 subunit alphacGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
go.drugbank.com/bio_entities/BE0001223TargetHumansCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process (PubMed:14592490, PubMed:21393242). Regulates angiogenesis by inhibitin...
Polypeptides: cGMP-inhibited 3',5'-cyclic phosphodiesterase 3BFunction: 3',5'-cyclic-AMP phosphodiesterase activityNAD-dependent protein deacylase sirtuin-5, mitochondrial
go.drugbank.com/bio_entities/BE0003362TargetHumansNAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693, PubMed:29180469). Activates CPS1 an...
Polypeptides: NAD-dependent protein deacylase sirtuin-5, mitochondrialSynonyms: SIR2-like protein 5, Regulatory protein SIR2 homolog 5Mitogen-activated protein kinase kinase kinase 5
go.drugbank.com/bio_entities/BE0018876TargetHumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determ...
Polypeptides: Mitogen-activated protein kinase kinase kinase 5Synonyms: MEKK 5, MEK kinase 5Very long chain fatty acid elongase 5
go.drugbank.com/bio_entities/BE0009375EnzymeTargetHumansCatalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- a...
Polypeptides: Very long chain fatty acid elongase 5Synonyms: ELOVL FA elongase 5, ELOVL fatty acid elongase 5T cell receptor beta variable 5-6
go.drugbank.com/bio_entities/BE0023691TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...
Polypeptides: T cell receptor beta variable 5-6Cardiolipin Biosynthesis CL(10:0/10:0/10:0/18:2(9Z,11Z))
smpdb.ca/view/SMP0175283MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.
Otilonium
go.drugbank.com/drugs/DB13500InvestigationalMixtures: DOLOSPAS 40 MG/80 MG FİLM KAPLI TABLET, 90 ADET, DOLOSPAS 40 MG/80 MG FİLM KAPLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDe Novo Triacylglycerol Biosynthesis TG(10:0/i-20:0/i-20:0)
smpdb.ca/view/SMP0032319MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
Cardiolipin Biosynthesis CL(10:0/15:0/i-20:0/i-20:0)
smpdb.ca/view/SMP0178107MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.