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Displaying results 4181 - 4190 of 10000 in total
  1. Target

    Aminoglycoside nucleotidyltransferase (4')

    go.drugbank.com/bio_entities/BE0003547
    EnzymeStaphylococcus aureus

    Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.

    Polypeptides: Aminoglycoside nucleotidyltransferase (4')Synonyms: ANT(4')
  2. Target

    Pepsin A-4

    go.drugbank.com/bio_entities/BE0012524
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-4Synonyms: Pepsinogen-4
  3. Target

    Interferon alpha-4

    go.drugbank.com/bio_entities/BE0012570
    TargetHumans

    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

    Polypeptides: Interferon alpha-4Synonyms: IFN-alpha-4
  4. Target

    NADPH oxidase 4

    go.drugbank.com/bio_entities/BE0019855
    TargetEnzymeHumans

    NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2 (PubMed:14966267, PubMed:15356101, PubMed:15927447, PubMed:21343298, PubMed:25062272). Can also catalyze to a smaller extent, the reduction of oxygen to superoxid...

    Polypeptides: NADPH oxidase 4
  5. Target

    NADH-ubiquinone oxidoreductase chain 6

    go.drugbank.com/bio_entities/BE0000348
    TargetHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:14595656, PubMed:8644...

    Polypeptides: NADH-ubiquinone oxidoreductase chain 6Synonyms: NADH dehydrogenase subunit 6
  6. Target

    Glucose-6-phosphate 1-dehydrogenase

    go.drugbank.com/bio_entities/BE0001089
    TargetHumans

    Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pe...

    Polypeptides: Glucose-6-phosphate 1-dehydrogenase
  7. Target

    6-phospho-beta-glucosidase BglT

    go.drugbank.com/bio_entities/BE0001390
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.

    Polypeptides: 6-phospho-beta-glucosidase BglTFunction: 6-phospho-beta-glucosidase activity
  8. Target

    Glucose-6-phosphate isomerase 2

    go.drugbank.com/bio_entities/BE0001469
    TargetGeobacillus stearothermophilus

    Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.

    Polypeptides: Glucose-6-phosphate isomerase 2Synonyms: Glucose-6-phosphate isomerase B
  9. Target

    Proteasome subunit beta type-6

    go.drugbank.com/bio_entities/BE0003919
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit beta type-6
  10. Target

    Eukaryotic translation initiation factor 6

    go.drugbank.com/bio_entities/BE0008972
    TargetHumans

    Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm (PubMed:10085284, PubMed:14654845, PubMed:21536732, PubMed:32669547). Behaves as a stimula...

    Polypeptides: Eukaryotic translation initiation factor 6Synonyms: eIF-6