Search

Displaying results 411 - 420 of 10000 in total
  1. Pathway

    Spermidine and Spermine Biosynthesis

    smpdb.ca/view/SMP0000445
    Metabolic

    Spermidine and spermine are produced in many tissues, as they are involved in the regulation of genetic processes from DNA synthesis to cell migration, proliferation, differentiation and apoptosis. … The Spermidine and Spermine Biosynthesis pathway highlights the creation of these cruicial polyamines.

    Drugs: Pyridoxal phosphate · Ademetionine · Spermine · Ornithine · Methionine · ATP +6 more
  2. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … , and others [L5968].

    Synonyms: o-acetoxybenzoic acid, O-acetylsalicylic acidInternational brands: Nu-seals
  3. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.

    Mixtures: AZARGA 10MG/ML+5MG/ML, AZARGA 10MG/ML + 5MG/MLCategories: Beta Blocking Agents, Non-Selective, and Thiazides, timolol and thiazides
  4. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications … greater potency than the R-enantiomer, but is metabolized at a higher rate.

    Mixtures: TARKA 180MG/2MG, TARKA 180MG/2MGCategories: Verapamil and analogues, trandolapril and verapamil
  5. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic … [L56092, A257419] Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DHFR) for activation, allowing it to function even when DHFR is inhibited by drugs like methotrexate

    Mixtures: NEO CROMATON BICOMPLESSOCategories: Enzymes and Coenzymes, Folic Acid and Derivatives
  6. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists. … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine

    Mixtures: NEO NAPACIN, NEO YEKASTHMACategories: Epinephrine and similars, Herbs and Natural Products
  7. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … It is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses.

    Mixtures: Tough Guy Hand Sanitizer Wipes Tough Guy, Gold Bond Pain and ItchCategories: Antiseptics and Disinfectants
  8. Drug

    Iron

    go.drugbank.com/drugs/DB01592
    ApprovedInvestigational

    A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. … Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia.

    Mixtures: Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo, HERREX FOL TABLETAS RECUBIERTAS 100MG/400Categories: Diet, Food, and Nutrition, multivitamins and iron
  9. Drug

    Dantrolene

    go.drugbank.com/drugs/DB01219
    ApprovedInvestigational

    Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.

    Categories: Dantrolene and DerivativesProducts: Dantrium Cap 25mg, Dantrium Cap 100mg
  10. Drug

    Pyrithione

    go.drugbank.com/drugs/DB06815
    ApprovedInvestigational

    Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as _Malassezia globosa_ and _M. restricta_ [A32162]. … It mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth [A27132].

    Mixtures: Head and Shoulders Dual Sachets Full and Strong, Head and Shoulders Dual Sachets Full and StrongSynonyms: Pyridinethiol N-oxide