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Cevimeline
go.drugbank.com/drugs/DB00185ApprovedCevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. … It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidineLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.[L5095]
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: ATIVAN® 1 MG TABLETAS, LORANS 1 TABLET 1 mgDofetilide
go.drugbank.com/drugs/DB00204ApprovedInvestigationalDofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidideTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigationalTrospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. … [L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.[L6211]
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: SPASMEX 5, TROSBIO® 30 MGRemikiren
go.drugbank.com/drugs/DB00212ExperimentalRemikiren is an orally active, high specificity renin inhibitor.
Categories: Heterocyclic Compounds, 1-RingOxyphenonium
go.drugbank.com/drugs/DB00219ApprovedIt is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem] … A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine.
International brands: A-SpasmGuanadrel
go.drugbank.com/drugs/DB00226ApprovedGuanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Aminosalicylic acid
go.drugbank.com/drugs/DB00233ApprovedInvestigationalThe sodium salt of the drug is better tolerated than the free acid.
Categories: 4-aminosalicylic acidSynonyms: 4-amino-2-hydroxybenzoic acid, 4-aminosalicylatePipobroman
go.drugbank.com/drugs/DB00236ApprovedAn antineoplastic agent that acts by alkylation.
Synonyms: N,N-bis-(3-bromopropionyl)-piperazine, 1,4-bis(3-bromopropionyl)piperazineCategories: Heterocyclic Compounds, 1-RingButabarbital
go.drugbank.com/drugs/DB00237ApprovedIllicitWithdrawnButabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates. … [A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-ethyl-5-(1-methylpropyl)barbituric acid, 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione