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Pentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: p,p'-(pentamethylenedioxy)dibenzamidine, 1,5-bis(4-amidinophenoxy)pentaneBelladonna
go.drugbank.com/drugs/DB13913ApprovedBelladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family _Solanaceae_. … The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb eye-drops by women to dilate the pupils of the eyes for aesthetic purposes.
Mixtures: ยาเม็ดตกเบ็ด 4., BIOGASTRIN TOZ, 60 GProducts: HE WEI PILLChamaecyparis obtusa wood oil
go.drugbank.com/drugs/DB14341InvestigationalChamaecyparis obtusa wood oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Ste-mediProducts: Phytoncide Su2-deoxyglucose
go.drugbank.com/drugs/DB08831InvestigationalWith respect to antiviral therapy, 2-deoxyglucose was shown to be effective against herpes simplex virus by affecting the virus' ability to penetrate cells. … Concerning the former, 2- deoxyglucose was used as an adjunct to chemotherapy and radiotherapy in the treatment of solid tumors (lung, breast, pancreas, head, neck, and gastric tumors).
Synonyms: 2-deoxy-D-glucose, 2-Deoxy-D-arabino-hexoseProtionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Categories: Heterocyclic Compounds, 1-RingDihydromorphine
go.drugbank.com/drugs/DB01565ExperimentalIllicitA semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds with 4 or More RingsCefalotin
go.drugbank.com/drugs/DB00456ApprovedVet approvedWithdrawnCefalotin is a cephalosporin antibiotic.
Synonyms: 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid, 7-(Thiophene-2-acetamido)cephalosporinCategories: Heterocyclic Compounds, 2-RingSevabertinib
go.drugbank.com/drugs/DB21667ApprovedInvestigational[L54638] It was granted accelerated approval by the FDA on November 19th, 2025.[L54608] … [L54638] Sevabertinib functions as a reversible kinase inhibitor of human epidermal growth factor receptor 2 (HER2), also exhibiting activity against epidermal growth factor receptor (EGFR).
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsPemivibart
go.drugbank.com/drugs/DB18720InvestigationalPemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain. … [L51733] Due to the amino acid substitutions in the Fc region (M435L/N441A), pemivibart has an extended serum half-life.[L51728]
Trypsin
go.drugbank.com/drugs/DB11237ApprovedInvestigationalVet approvedWhen converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine … Trypsin contains a nucleophilic residue Ser in the enzyme active site which attacks the carbonyl moiety of the substrate peptide bond to form an acyl-enzyme intermediate [A27241].