Search

Displaying results 4261 - 4270 of 10000 in total
  1. Target

    Integrin alpha-4

    go.drugbank.com/bio_entities/BE0000590
    TargetHumans

    Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. … Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.

    Polypeptides: Integrin alpha-4Synonyms: VLA-4 subunit alpha
  2. Target

    Integrin beta-4

    go.drugbank.com/bio_entities/BE0003298
    TargetHumans

    Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.

    Polypeptides: Integrin beta-4
  3. Target

    4-hydroxymandelate synthase

    go.drugbank.com/bio_entities/BE0004115
    TargetAmycolatopsis orientalis

    Required to synthesize hydroxyphenylglycine, a recurring skeletal component of nonproteinogenic macrocyclic peptide antibiotics such as vancomycin.

    Polypeptides: 4-hydroxymandelate synthaseSynonyms: 4-hydroxyphenylpyruvate dioxygenase II
  4. Target

    Phosphodiesterase isozyme 4

    go.drugbank.com/bio_entities/BE0009697
    TargetHumans

    Polypeptides: Phosphodiesterase isozyme 4
  5. Target

    P2Y purinoceptor 4

    go.drugbank.com/bio_entities/BE0009822
    TargetHumans

    Receptor for UTP and UDP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP

    Polypeptides: P2Y purinoceptor 4
  6. Target

    Prolyl 4-hydroxylase

    go.drugbank.com/bio_entities/BE0009980
    EnzymeHumans

    Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins … Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins

    Polypeptides: Prolyl 4-hydroxylase subunit alpha-1, Prolyl 4-hydroxylase subunit alpha-2Synonyms: 4-PH alpha-1, 4-PH alpha-2
  7. Drug

    Magrolimab

    go.drugbank.com/drugs/DB16225
    Investigational

    Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

    Synonyms: Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma.4-chain), disulfide with human-mus musculus monoclonal hu5f9-g4 .kappa.-chain, dimer, )) (8.8.10) (1-117)-homo sapiens ighg4*01 (ch1 (118-2
  8. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Mixtures: Ed-A-hist Pse, GRIPORT 650 MG/4 MG/ 60 MG FILM KAPLI TABLET ,20 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic alpha-1 Receptor Agonists
  9. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.

    Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideMixtures: Dexlido M-C, Mlk F4-C
  10. Drug

    Rupatadine

    go.drugbank.com/drugs/DB11614
    ApprovedInvestigational

    Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria … It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: RUPAFIN® 10 MG, RUPATADINA EG