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Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z)/16:0)
smpdb.ca/view/SMP0288057MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Phosphatidylcholine Biosynthesis PC(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0014936MetabolicPhosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...
Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 morePhosphatidylethanolamine Biosynthesis PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:4(7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0015832MetabolicPhosphatidylserine, itself, is synthesized using a base-exchange reaction with phosphatidylcholine.
Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 moreAcylcarnitine (10Z,12Z)-octadeca-10,12-dienoylcarnitine
smpdb.ca/view/SMP0123615Metabolic(10Z,12Z)-octadeca-10,12-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z,12Z)-octadeca-10,12-dienoyl-CoA reacts with L-carnitine to form (10Z,12Z)-octadeca-10,12-dienoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine (8Z,10E)-Dodeca-8,10-dienoylcarnitine
smpdb.ca/view/SMP0124037Metabolic(8Z,10E)-Dodeca-8,10-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (8Z,10E)-dodeca-8,10-dienoyl-CoA reacts with L-carnitine to form (8Z,10E)-dodeca-8,10-dienoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine (10E,13E)-Nonadeca-10,13-dienoylcarnitine
smpdb.ca/view/SMP0124357Metabolic(10E,13E)-Nonadeca-10,13-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10E,13E)-Nonadeca-10,13-dienoyl-CoA reacts with L-carnitine to form (10E,13E)-Nonadeca-10,13-dienoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreMargetuximab
go.drugbank.com/drugs/DB14967ApprovedInvestigational[A225751, A225756, A225766, A191829, L27986] Margetuximab binds to the same epitope on the HER2 extracellular domain and induces the same effects as [trastuzumab]. … [A225751, A225756, A225766, A191829, L27986] Margextuximab was granted FDA approval on December 16, 2020, and is currently marketed under the trademark MARGENZA™ by MacroGenics, Inc.[L27986]
Antrafenine
go.drugbank.com/drugs/DB01419ApprovedIt is not widely used as it has largely been replaced by newer drugs. … Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen.
Acylcarnitine (10Z,13Z)-Nonadeca-10,13-dienoylcarnitine
smpdb.ca/view/SMP0124359Metabolic(10Z,13Z)-Nonadeca-10,13-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z,13Z)-Nonadeca-10,13-dienoyl-CoA reacts with L-carnitine to form (10Z,13Z)-Nonadeca-10,13-dienoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreCardiolipin Biosynthesis CL(10:0/10:0/10:0/10:0)
smpdb.ca/view/SMP0175274MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...