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Displaying results 421 - 430 of 4238 in total
  1. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.

  2. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is also used as a coagulant in the water purification process. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

  3. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone. … Salts of undecylenate are found in topical over-the-counter or mixture products as antifungal agents.

  4. Drug

    Oxilofrine

    go.drugbank.com/drugs/DB11610
    Approved

    Oxilofrine is used in combination with [DB11609] as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.

  5. Drug

    Clascoterone

    go.drugbank.com/drugs/DB12499
    ApprovedInvestigational

    [L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia.[A218766] … [A218771] By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland

  6. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.

    Mixtures: Au Kah Chuen Skin Lotion
  7. Drug

    Chlorphentermine

    go.drugbank.com/drugs/DB01556
    ApprovedIllicitWithdrawn

    A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.

  8. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990[L5962].

    Products: Flonase Aem-sus 50mcg/aem, Flonase - Aem-sus Nas 50mcg/md
  9. Drug

    Phenyltoloxamine

    go.drugbank.com/drugs/DB11160
    Approved

    Phenyltoloxamine acts as an adjuvant analgesic, which augments the analgesic effect of acetaminophen. It also potentiates the effects of other drugs, such as codeine and codeine derivatives. … early as the 1950s) first-generation antihistamines were not optimally investigated [A32705].

  10. Drug

    Sodium iodide

    go.drugbank.com/drugs/DB11119
    ApprovedInvestigational

    Radiolabelled compound, [DB09293], is used as a diagnostic tool to evaluate thyroid function and morphology. … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine.