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Displaying results 4311 - 4320 of 10000 in total
  1. Drug

    Isoflavone

    go.drugbank.com/drugs/DB12007
    ApprovedInvestigationalWithdrawn

    , type II diabetes mellitus, and breast and prostate cancer [A33099]. … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean

  2. Drug

    XEN-2174

    go.drugbank.com/drugs/DB05012
    Experimental

    In episodes of pain, inhibition of NET by XEN-2174 elevates the levels of NE leading to the activation of inhibitory pathways preventing pain signals from reaching the brain. … XEN-2174 is a synthetic drug modeled on a peptide from the venom of a cone shell found on Australia's Great Barrier Reef.

    Categories: Amino Acids, Peptides, and Proteins
  3. Drug

    Larazotide

    go.drugbank.com/drugs/DB05645
    Investigational

    An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    UB-612

    go.drugbank.com/drugs/DB16444
    Investigational

    The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components[L30653]. … It was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658].

    Synonyms: UB-612 COVID-19, UB-612 COVID-19 vaccine
  5. Drug

    Epicept NP-1

    go.drugbank.com/drugs/DB05492
    Investigational

    The peripheral nervous system includes nerves that run from the brain and spinal cord to the rest of the body. … EpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used antidepressant) and ketamine (an NMDA antagonist that is used as an anesthetic).

  6. Drug

    Toluene

    go.drugbank.com/drugs/DB11558
    InvestigationalVet approved

    It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.

  7. Drug

    Demecarium

    go.drugbank.com/drugs/DB00944
    Approved

    Demecarium inactivates both pseudocholinesterase and acetylcholinesterase. In the eye, this causes constriction of the iris sphincter muscle (causing miosis) and the ciliary muscle. … Demecarium is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase.

    Categories: Antiglaucoma Preparations and Miotics
  8. Drug

    MK-8245

    go.drugbank.com/drugs/DB13024
    Investigational

    MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.

  9. Drug

    Dipyrithione

    go.drugbank.com/drugs/DB11327
    Approved

    Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available. … [L2615] Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as _Malassezia globosa_ and _M. restricta_.[A32162]

  10. Drug

    Bovine type I collagen

    go.drugbank.com/drugs/DB10771
    ApprovedInvestigational

    skin tears) and draining wounds [L2500]. … Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing [L2427], [L2450].