Search
Selegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: L-DeprenalinMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease
Mixtures: EMAXIN BASLANGIC SETI, 7+7+7+7 ADET, EMAXIN BASLANGIC SETI, 7+7+7+7 ADETCategories: N-methyl-D-aspartate Receptor Antagonist, Cytochrome P-450 CYP2A6 InhibitorsFluocinonide
go.drugbank.com/drugs/DB01047ApprovedInvestigationalA topical glucocorticoid used in the treatment of eczema.
Mixtures: TOPSYN-Y, Fluocinonide 0.05% / Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersNovobiocin
go.drugbank.com/drugs/DB01051ApprovedInvestigationalVet approvedWithdrawnNovobiocin is an antibiotic compound derived from _Streptomyces niveus_. It has a chemical structure similar to coumarin. … (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamideNitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Mixtures: ENEAS® 10/20 MG COMPRIMIDOS, ENEAS® 10/20 MG COMPRIMIDOSCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEchothiophate
go.drugbank.com/drugs/DB01057ApprovedInvestigationalA potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.
Synonyms: 2-(Diethoxyphosphorylsulfanyl)ethyl-N,N,N-trimethylazanium iodideOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalIt is often used as first-line therapy for OAB.[A185990] … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolateAcetophenazine
go.drugbank.com/drugs/DB01063ApprovedAcetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. … It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Categories: Heterocyclic Compounds, 3-RingIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline]. … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion
Categories: Adrenergic beta-2 Receptor Agonists, Compounds used in a research, industrial, or household settingSynonyms: N-isopropyl-β-dihydroxyphenyl-β-hydroxyethylamine, 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanolGlipizide
go.drugbank.com/drugs/DB01067ApprovedInvestigational®. … Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea, N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea