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NNZ-2591
go.drugbank.com/drugs/DB15601Investigational[L11106] It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and Pitt Hopkins Syndromes. … NNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been
Midecamycin
go.drugbank.com/drugs/DB13456InvestigationalIn this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar.
Synonyms: Turimycin P3Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseFlucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Floxapen 2g Pulver zur Herstellung einer Injektions- bzw. Infusionslösung, Flucloxacillin WABO 1 g Pulver zur Herstellung einer Injektions-/InfusionslösungPearl (hyriopsis cumingii)
go.drugbank.com/drugs/DB14249InvestigationalPearl (hyriopsis cumingii) is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Ma Ying Long HemorrhoidalAtenolol Action Pathway
smpdb.ca/view/SMP0000298Drug actionAtenolol, trade name Tenormin, is a beta blocker prescribed to treat hypertension. Atenolol is a selective beta-1-adrenoceptor antagonist targeting the heart and vascular smooth muscle to inhibit sympathetic activity. Binding of atenolol...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Bisoprolol Action Pathway
smpdb.ca/view/SMP0000300Drug actionBisoprolol (also known as Zebeta) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to reduced heart ...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Metoprolol Action Pathway
smpdb.ca/view/SMP0000302Drug actionMetoprolol (also known as Lopressor) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Metoprolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of o...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Pindolol Action Pathway
smpdb.ca/view/SMP0000306Drug actionPindolol (also known as Visken) a beta blocker (non-selective) that block beta-1 adrenergic receptor in heart. … Blocking beta-1 adrenergic receptor could prevent the binding of epinephrine and norepinephrine, which could efficiently reduce blood pressure and heart rate.
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Procainamide (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000324Drug actionThis drug may be administered intravenously to treat supraventricular and ventricular arrhythmias. It is better tolerated intravenously than quinidine.
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Fosphenytoin (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000326Drug actionThis pathway illustrates the fosphenytoin targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cell...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2