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5-hydroxytryptamine receptor 6
go.drugbank.com/bio_entities/BE0000945TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:36989299, PubMed:37327704, PubMed
Polypeptides: 5-hydroxytryptamine receptor 6Synonyms: Serotonin receptor 6Beta-3 adrenergic receptor
go.drugbank.com/bio_entities/BE0001012TargetHumansG protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively (PubMed
Polypeptides: Beta-3 adrenergic receptorFunction: beta-adrenergic receptor activityOxysterols receptor LXR-beta
go.drugbank.com/bio_entities/BE0001598TargetHumansNuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
Polypeptides: Oxysterols receptor LXR-betaSynonyms: Liver X receptor beta, Nuclear receptor NEREstrogen-related receptor gamma
go.drugbank.com/bio_entities/BE0002088TargetHumansOrphan receptor that acts as a transcription activator in the absence of bound ligand.
Polypeptides: Estrogen-related receptor gammaSynonyms: Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3Metabotropic glutamate receptor 3
go.drugbank.com/bio_entities/BE0002342TargetHumansG protein-coupled receptor for glutamate.
Polypeptides: Metabotropic glutamate receptor 3Melanocyte-stimulating hormone receptor
go.drugbank.com/bio_entities/BE0002447TargetHumansG protein-coupled receptor that binds melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and adrenocorticotropic hormone/ACTH, which are peptide products of the POMC precursor protein (PubMed … MC1R interacts with G protein-coupled receptor opsin 3/OPN3, which couples to G(i) proteins and inhibits the alpha-MSH-induced cAMP response, thereby reducing melanin synthesis (PubMed:31097585).
Polypeptides: Melanocyte-stimulating hormone receptorSynonyms: Melanocortin receptor 1Anthrax toxin receptor 2
go.drugbank.com/bio_entities/BE0003223TargetHumansNecessary for cellular interactions with laminin and the extracellular matrix
Polypeptides: Anthrax toxin receptor 2Function: transmembrane signaling receptor activityLeukotriene B4 receptor 1
go.drugbank.com/bio_entities/BE0003490TargetHumansReceptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. … Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response
Polypeptides: Leukotriene B4 receptor 1Synonyms: G protein-coupled receptor 16, Chemoattractant receptor-like 1Somatostatin receptor type 2
go.drugbank.com/bio_entities/BE0003528TargetHumansReceptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. … Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization
Polypeptides: Somatostatin receptor type 2Prostaglandin D2 receptor 2
go.drugbank.com/bio_entities/BE0003561TargetHumansReceptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. … Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses
Polypeptides: Prostaglandin D2 receptor 2Synonyms: G protein-coupled receptor 44, Chemoattractant receptor-homologous molecule expressed on Th2 cells