Estrogen-related receptor gamma

BE0002088ProteinHumansESRRG

Orphan receptor that acts as a transcription activator in the absence of bound ligand. It is acted on by 30 drugs in DrugBank.

Gene name
ESRRG
UniProtKB entry
P62508Swiss-Prot
Cellular location
Nucleus
Residues / weight
458 residues · 51,305 Da
Also known as
ERR gamma-2 · ERR3 · ERRG2 · Estrogen receptor-related protein 3 · KIAA0832

Resolves to

Protein
UniProtP62508UniProt nameERR3_HUMAN
Gene
HGNCHGNC:3474NCBI Gene2104GenBank4092075GeneCardsESRRG
Pharmacology
IUPHAR/GtoPdb624KEGGhsa:2104
Structure
PDB1KV6PDB1TFCPDB1VJB
Drugs

What you can answer from here — as of September 07, 2019

30DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
13GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
64+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Estrogen-related receptor gamma, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In