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Displaying results 4391 - 4400 of 10000 in total
  1. Drug

    Vecuronium

    go.drugbank.com/drugs/DB01339
    ApprovedInvestigational

    A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or

    Categories: P-glycoprotein substratesProducts: BROMURO DE VECURONIO 4 MG/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, BLOK-L 4 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET
  2. Pathway

    Acylcarnitine (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123485
    Metabolic

    -2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoylcarnitine. … inner membrane to once again form (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3-oxocyclopentyl]hept-5-enoyl-CoA and L-carnitine. (5Z)-7-[(1R,2E,5S)-5-hydroxy-2-[(2E)-oct-2-en-1-ylidene]-3

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Acetyl-CoA carboxylase 1
  3. Drug

    Fosaprepitant

    go.drugbank.com/drugs/DB06717
    ApprovedInvestigational

    Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.

    Categories: Neurokinin 1 Antagonists, Substance P/Neurokinin-1 Receptor AntagonistProducts: BRIAN EX, APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  4. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting … Tropisetron is an indole derivative with antiemetic activity.

    Categories: Serotonin 5-HT3 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - Kapseln
  5. Drug

    Upanovimab

    go.drugbank.com/drugs/DB16505
    Investigational

    Upanovimab (SCTA01) was under investigation in clinical trials (NCT04683328, NCT04644185, NCT04709328 and NCT05156645) to evaluate its safety and efficacy in patients with severe COVID-19

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL SCTA01 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SCTA01 .Categories: Experimental Unapproved Treatments for COVID-19
  6. Drug

    Aklavine

    go.drugbank.com/drugs/DB19070
    Experimental

    Aklavine is under investigation in clinical trial NCT03026842 (Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With T(8;21)).

    Synonyms: 1-naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-.alpha.-l-lyxo-hexopyranosyl)oxy)-, methyl ester, (1r,2r,4s)-, Aclacinomycin t
  7. Pathway

    Acylcarnitine (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123569
    Metabolic

    -1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine. … (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Acetyl-CoA carboxylase 1
  8. Drug

    DOTMP SM-153

    go.drugbank.com/drugs/DB18484
    Investigational

    Synonyms: Samarate(5-)-153sm, ((((1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-.kappa.n1,.kappa.n4,.kappa.n7,.kappa.n10)tetrakis(methylene))tetrakis(phosphonato-.kappa.o))(8-))-, pentahydrogen
  9. Drug

    Crotonaldehyde

    go.drugbank.com/drugs/DB04381
    Experimental

    Synonyms: (E)-crotonaldehyde, 1-formylpropene
  10. Drug

    Retlirafusp alfa

    go.drugbank.com/drugs/DB17517
    Investigational

    Synonyms: protein with peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor (human isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal, Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion