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Displaying results 4481 - 4490 of 10000 in total
  1. Drug

    Somatrogon

    go.drugbank.com/drugs/DB14960
    ApprovedInvestigational

    [A241515] Recombinant growth hormone therapy for growth hormone deficiency and other conditions has been available since 1985, with daily administration being the standard treatment for many years. … C-terminus of human growth hormone.

    Synonyms: Recombinant human growth hormone long acting (fused w beta chains of HCG), .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES OF HUMAN CHORIOGONADOTROPIN SUBUNIT .BETA. (CG-.BETA.)-(118-145)- PEPTIDE (220-247Products: NGENLA 24 MG/1,2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET, NGENLA 60 MG/1,2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET
  2. Drug

    Cipepofol

    go.drugbank.com/drugs/DB16295
    ApprovedInvestigational

    of anesthetics while reducing the injection pain and respiratory depression that have long been recognized as limitations of intravenous anesthesia. … GABA-A receptors, similar to the previously approved [propofol].

  3. Drug

    Polymyxin B

    go.drugbank.com/drugs/DB00781
    ApprovedInvestigationalVet approved

    Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label].

    Synonyms: Polymyxin B, Polimixina BInternational brands: Polomyxin B
  4. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell. … AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells.

  5. Target

    Cytohesin-3

    go.drugbank.com/bio_entities/BE0004433
    TargetHumans

    Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity)

    Synonyms: General receptor of phosphoinositides 1
  6. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding … [T894, T322] Additionally, third-generation cephalosporins have been shown to have more stability in the presence of beta-lactamases compared to first- and second-generation cephalosporins.

    Mixtures: MOLCEF PLUS 100/62.5/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, MOLCEF PLUS 200 MG+62.5/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Ifenprodil

    go.drugbank.com/drugs/DB08954
    ApprovedInvestigationalWithdrawn

    N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function. … A220128] Although ifenprodil has received considerable interest in its potential neuromodulatory activities in psychiatric conditions, including dependency[A220138] and depression,[A220143] it has also been

    Categories: Heterocyclic Compounds, 1-Ring, NMDA Receptor Antagonists
  8. Drug

    Lysergic acid diethylamide

    go.drugbank.com/drugs/DB04829
    IllicitInvestigational

    Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. … Many emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience.

    Categories: Serotonin 5-HT2 Receptor Agonists, Cytochrome P-450 SubstratesSynonyms: N,N-diethyl-D-lysergamide, N,N-diethyllysergamide
  9. Drug

    MM-093

    go.drugbank.com/drugs/DB05512
    Investigational

    The presence of hAFP in the pregnant mother’s blood has long been associated with remission of many autoimmune diseases, including rheumatoid arthritis, psoriasis and multiple sclerosis, during the third … Current studies are assessing MM-093’s potential to improve the treatment of autoimmune disease.

  10. Target

    Elongation factor 1-alpha 1

    go.drugbank.com/bio_entities/BE0004528
    TargetHumans

    Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis (PubMed:26593721, PubMed:26651998, PubMed:36123449, PubMed:362...

    Synonyms: Leukocyte receptor cluster member 7