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Displaying results 441 - 450 of 10000 in total
  1. Target

    Nociceptin receptor

    go.drugbank.com/bio_entities/BE0002378
    TargetHumans

    G protein-coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin.

    Polypeptides: Nociceptin receptorSynonyms: Orphanin FQ receptor, Kappa-type 3 opioid receptor
  2. Target

    Thrombopoietin receptor

    go.drugbank.com/bio_entities/BE0003440
    TargetHumans

    Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation.

    Polypeptides: Thrombopoietin receptorFunction: thrombopoietin receptor activity
  3. Target

    Poliovirus receptor

    go.drugbank.com/bio_entities/BE0004247
    TargetHumans

    Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological sy...

    Polypeptides: Poliovirus receptor
  4. Target

    NMDA receptor

    go.drugbank.com/bio_entities/BE0004956
    TargetHumans

    Forms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits. … Forms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits (PubMed:38598639).

    Polypeptides: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2ASynonyms: Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1
  5. Target

    Somatostatin receptor

    go.drugbank.com/bio_entities/BE0010008
    TargetHumans

  6. Target

    Fibronectin receptor

    go.drugbank.com/bio_entities/BE0010279
    TargetHumans

    Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. … ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430).

    Synonyms: Fibronectin receptor subunit alpha, Fibronectin receptor subunit beta
  7. Target

    Adiponectin receptor

    go.drugbank.com/bio_entities/BE0010287
    TargetHumans

    Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). … Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis.

    Polypeptides: Adiponectin receptor protein 1, Adiponectin receptor protein 2Synonyms: Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I
  8. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    Despite being banned in the United States, fenproporex has been described as the second most commonly consumed appetite suppressant worldwide, [6] with fenproporex containing anorectics still being commonly … In 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers.

    International brands: Desobesi-MProducts: IFA-DIETY A. P.
  9. Drug

    Lifileucel

    go.drugbank.com/drugs/DB17107
    ApprovedInvestigational

    Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived T cells from the patient [L50171] which undergo isolation, ex vivo expansion, and activation[A263341

    Categories: Antineoplastic cell and gene therapy
  10. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). … [A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L.

    Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL)International brands: Stieva-A