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Displaying results 4501 - 4510 of 10000 in total
  1. Target

    Electrogenic sodium bicarbonate cotransporter 4

    go.drugbank.com/bio_entities/BE0004677
    TransporterHumans

    Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3

    Polypeptides: Electrogenic sodium bicarbonate cotransporter 4Synonyms: Solute carrier family 4 member 5
  2. Target

    DNA topoisomerase 4 subunit B

    go.drugbank.com/bio_entities/BE0008386
    TargetBacillus subtilis (strain 168)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit B
  3. Target

    Secreted frizzled-related protein 4

    go.drugbank.com/bio_entities/BE0009094
    TargetHumans

    They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. … May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity).

    Polypeptides: Secreted frizzled-related protein 4Synonyms: sFRP-4
  4. Target

    Sphingolipid delta(4)-desaturase DES1

    go.drugbank.com/bio_entities/BE0011584
    TargetHumans

    Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338).

    Polypeptides: Sphingolipid delta(4)-desaturase DES1
  5. Target

    Transcriptional enhancer factor TEF-4

    go.drugbank.com/bio_entities/BE0014575
    TargetHumans

    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. … The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1

    Polypeptides: Transcriptional enhancer factor TEF-4
  6. Drug

    Ubidecarenone

    go.drugbank.com/drugs/DB09270
    ApprovedInvestigationalNutraceutical

    [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.

    Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Xyzbac GCategories: P-glycoprotein substrates
  7. Drug

    Calfactant

    go.drugbank.com/drugs/DB06415
    ApprovedInvestigational

    It adsorbs to the air:fluid interface in the lungs and works to reduce surface tension, in a manner similar to endogenous pulmonary surfactant. … proteins B and C.

    Synonyms: SF-RI 1Products: INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON ,6 ML, INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON,3 ML
  8. Drug

    Bicisate

    go.drugbank.com/drugs/DB11164
    Approved

    Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029]

    Products: MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADET, Neurolite Kit für ein radioaktives Arzneimittel zur Herstellung einer [99mTc]Technetium–Bicisat- Injektionslösung
  9. Drug

    Albumin human

    go.drugbank.com/drugs/DB00062
    ApprovedInvestigational

    This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. … Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III).

    Products: Pulmocis 2 mg Kit für ein radioaktives Arzneimittel, NANOTOP 0,5 mg Kit für ein radioaktives Arzneimittel
  10. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]

    Mixtures: OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA, NuDroxiPAK M-15Categories: COX-2 Inhibitors, Cytochrome P-450 Substrates