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Secreted frizzled-related protein 4
go.drugbank.com/bio_entities/BE0009094TargetHumansThey have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. … May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity).
Polypeptides: Secreted frizzled-related protein 4Synonyms: sFRP-4Sphingolipid delta(4)-desaturase DES1
go.drugbank.com/bio_entities/BE0011584TargetHumansHas sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338).
Polypeptides: Sphingolipid delta(4)-desaturase DES1Transcriptional enhancer factor TEF-4
go.drugbank.com/bio_entities/BE0014575TargetHumansTranscription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. … The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
Polypeptides: Transcriptional enhancer factor TEF-4Horseradish
go.drugbank.com/drugs/DB10674ApprovedHorseradish allergenic extract is used in allergenic testing.
Products: Nwk A-FVFrovatriptan
go.drugbank.com/drugs/DB00998ApprovedFrovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: FROVATRIPTAN EG, NEWART 2.5 MG TABLET, 3 ADETOcrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigationalsuch as a doctor's office. … [A18875,A251745] MS is a chronic, inflammatory, autoimmune disease of the central nervous system that leads to neurological disabilities and a significantly reduced quality of life.
Products: OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET, OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETBicisate
go.drugbank.com/drugs/DB11164ApprovedBicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029]
Products: MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADET, Neurolite Kit für ein radioaktives Arzneimittel zur Herstellung einer [99mTc]Technetium–Bicisat- InjektionslösungAlbumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalThis is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. … Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III).
Products: Pulmocis 2 mg Kit für ein radioaktives Arzneimittel, NANOTOP 0,5 mg Kit für ein radioaktives ArzneimittelVascular endothelial growth factor A, long form
go.drugbank.com/bio_entities/BE0000163TargetHumansParticipates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)
Polypeptides: Vascular endothelial growth factor A, long form3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0001856TargetPseudomonas mevaloniiP.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductase