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Displaying results 4561 - 4570 of 10000 in total
  1. Target

    Glutamate receptor 2

    go.drugbank.com/bio_entities/BE0000829
    TargetHumans

    Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid (Pub...

    Polypeptides: Glutamate receptor 2Synonyms: GluR-2, AMPA-selective glutamate receptor 2
  2. Target

    Thiamine transporter 2

    go.drugbank.com/bio_entities/BE0000963
    TransporterHumans

    Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism (PubMed:11731220, PubMed:33008889, PubMed:35512554, PubMed:35724964). Has no folate transport activity (PubMed:11731220). Mediates H(+)-dependent pyridoxin...

    Polypeptides: Thiamine transporter 2Synonyms: ThTr-2
  3. Target

    Integrin beta-2

    go.drugbank.com/bio_entities/BE0001041
    TargetHumans

    Integrin ITGAL:ITGB2 is a receptor for ICAM1, ICAM2 and ICAM3 (PubMed:1676048, PubMed:23775590, PubMed:38195629). Integrin ITGAL:ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated ...

    Polypeptides: Integrin beta-2
  4. Target

    Alpha-2-antiplasmin

    go.drugbank.com/bio_entities/BE0001125
    TargetHumans

    Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin

    Polypeptides: Alpha-2-antiplasminSynonyms: Alpha-2-AP, Alpha-2-PI
  5. Target

    L-asparaginase 2

    go.drugbank.com/bio_entities/BE0001351
    TargetEscherichia coli (strain K12)

    Polypeptides: L-asparaginase 2
  6. Target

    Methionine aminopeptidase 2

    go.drugbank.com/bio_entities/BE0001534
    TargetHumans

    Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The...

    Polypeptides: Methionine aminopeptidase 2Synonyms: MAP 2, MetAP 2
  7. Target

    Nucleoside 2-deoxyribosyltransferase

    go.drugbank.com/bio_entities/BE0002706
    TargetLactobacillus helveticus

    Polypeptides: Nucleoside 2-deoxyribosyltransferase
  8. Target

    Interferon alpha-2

    go.drugbank.com/bio_entities/BE0003450
    TargetHumans

    Produced by macrophages, IFN-alpha have antiviral activities

    Polypeptides: Interferon alpha-2Synonyms: IFN-alpha-2
  9. Target

    Prostaglandin reductase 2

    go.drugbank.com/bio_entities/BE0003560
    TargetHumans

    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2 (PubMed:19000823). Overexpression represses transcriptional activ...

    Polypeptides: Prostaglandin reductase 2Synonyms: PRG-2
  10. Target

    Peptide deformylase 2

    go.drugbank.com/bio_entities/BE0003875
    TargetBacillus cereus (strain ATCC 14579 / DSM 31)

    Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity ...

    Polypeptides: Peptide deformylase 2Synonyms: PDF 2, Polypeptide deformylase 2