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Diiodohydroxyquinoline
go.drugbank.com/drugs/DB09115ApprovedDiiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown. … Iodoquinol is not currently available in any FDA-approved products.
Mixtures: Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%, Alcortin ACategories: Heterocyclic Compounds, 2-RingPemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnPemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. … Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
Categories: Heterocyclic Compounds, 1-RingNorclozapine
go.drugbank.com/drugs/DB05766InvestigationalACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia.
Synonyms: N-DesmethylclozapineCategories: Heterocyclic Compounds, 3-RingPhenylacetic acid
go.drugbank.com/drugs/DB09269ApprovedPhenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. … Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.
Synonyms: ANTINEOPLASTON AS 2-1 COMPONENT PHENYLACETIC ACID, α-toluic acidAcetylcholine
go.drugbank.com/drugs/DB03128ApprovedInvestigationalA neurotransmitter. … Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in
Synonyms: O-AcetylcholineProducts: Miochol E, MIOCHOL ECorynebacterium diphtheriae
go.drugbank.com/drugs/DB09877ApprovedInvestigationalThe bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. … *Corynebacterium diphtheriae* toxin is extracted from the pathogenic actinobacterium *C. diphtheriae* that causes diphtheria.
Cusatuzumab
go.drugbank.com/drugs/DB15100Investigational[A241975] Cusatuzumab is a humanized IgG1 antibody targeted against CD70. … CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival.
Human umbilical cord blood mononuclear cell-conditioned medium
go.drugbank.com/drugs/DB15724ExperimentalThen, the medium is filtered and separated from the HUCBCs. … Thus, the media in which they are cultured is believed to also have therapeutic potential.
Caroxazone
go.drugbank.com/drugs/DB09254ApprovedWithdrawnCaroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. … However, it presents a five-fold preference for the MAO-B subtype.
Categories: Heterocyclic Compounds, 1-Ring