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Displaying results 4631 - 4640 of 10000 in total
  1. Drug

    Exametazime

    go.drugbank.com/drugs/DB11179
    Approved

    It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes.

    Products: CERETEC FOR INJECTION 0.5 mg/vial, BRAIN - SPECT®
  2. Drug

    Praziquantel

    go.drugbank.com/drugs/DB01058
    ApprovedInvestigationalVet approved

    Specifically, it is known as a treatment of trematodes and cestodes infections such as schistosomiasis, taeniasis, and cysticercosis. … [A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: DISTOCIDE TABLET 600 mg, CISTICID ® 600MG
  3. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% EProducts: GLICINA IRRIGACION 1.5% M/V, GLICINA IRRIGACION USP (1.5% W/V)BOLSA POR 3000 ML
  4. Drug

    Benzbromarone

    go.drugbank.com/drugs/DB12319
    ApprovedWithdrawn

    Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2C19 InhibitorsSynonyms: 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
  5. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    It has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. … Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes [A27248], and the inhibition of melanin synthesis at non-toxic concentrations was observed _in vitro_.

    Mixtures: Dr G Whitening REFORMER by EGF, Dr G Whitening FORTIFIER by EGFSynonyms: hydroquinone O-β-D-glucopyranoside, p-hydroxyphenyl β-D-glucoside
  6. Drug

    Efgartigimod alfa

    go.drugbank.com/drugs/DB15270
    ApprovedInvestigational

    [A243759,A243784] Efgartigimod alfa is a first-in-class[L39501] antagonist of the neonatal Fc receptor (FcRn) used in the treatment of MG. … [L39496] IgG antibodies, including the autoantibodies responsible for MG symptoms, can be 'recycled', a process that significantly extends their half-life by evading lysosomal degradation via binding with

    Categories: Human Immunoglobulin G
  7. Pathway

    Acylcarnitine (9E,12Z)-10-nitrooctadeca-9,12-dienoylcarnitine

    smpdb.ca/view/SMP0123547
    Metabolic

    (9E,12Z)-10-nitrooctadeca-9,12-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (9E,12Z)-10-nitrooctadeca-9,12-dienoyl-CoA reacts with L-carnitine to form (9E,12Z)-10-nitrooctadeca-9,12-dienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  8. Target

    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

    go.drugbank.com/bio_entities/BE0000051
    TargetEnzymeHumans

    A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis.

    Polypeptides: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1Synonyms: Delta-5-3-ketosteroid isomerase, 3-beta-hydroxy-5-ene steroid dehydrogenase
  9. Target

    G protein-coupled receptor family C group 5 member D

    go.drugbank.com/bio_entities/BE0010290
    TargetHumans

    G protein-coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails

    Polypeptides: G protein-coupled receptor family C group 5 member D
  10. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

    Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET