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Displaying results 4661 - 4670 of 10000 in total
  1. Drug

    Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen

    go.drugbank.com/drugs/DB15683
    ApprovedInvestigational

  2. Drug

    Umifenovir

    go.drugbank.com/drugs/DB13609
    Investigational

    [A191475] Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational … [A191475] It has been in use in Russia for approximately 25 years and in China since 2006.

  3. Drug

    Polythiazide

    go.drugbank.com/drugs/DB01324
    Approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)

    Categories: polythiazide and potassium, Genito Urinary System and Sex Hormones
  4. Drug

    Xamoterol

    go.drugbank.com/drugs/DB13781
    Approved

    It modulates the sympathetic control of the heart but has no agonist action on β2-adrenoceptors. … Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients.

  5. Target

    Alpha-ketoglutarate-dependent dioxygenase FTO

    go.drugbank.com/bio_entities/BE0005795
    TargetHumans

    Demethylation of m6A(m) in the 5'-cap by FTO affects mRNA stability by promoting susceptibility to decapping (PubMed:28002401). … Ability to repair alkylated DNA and RNA is however unsure in vivo (PubMed:18775698, PubMed:20376003).

    Synonyms: Fat mass and obesity-associated protein
  6. Indication

    Acute Myocardial Infarction (AMI)

    go.drugbank.com/conditions/DBCOND0032772
    Drugs: Clopidogrel · Lisinopril · Reteplase · Streptokinase · Zofenopril
    Synonyms: Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
  7. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms … Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists.

    Categories: Serotonin-1b and Serotonin-1d Receptor Agonist
  8. Drug

    Tiludronic acid

    go.drugbank.com/drugs/DB01133
    ApprovedVet approvedWithdrawn

    Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and [clodronic acid]. … [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763]

    Categories: Drugs Affecting Bone Structure and Mineralization
  9. Drug

    Neisseria meningitidis group Y capsular polysaccharide tetanus toxoid conjugate antigen

    go.drugbank.com/drugs/DB15682
    ApprovedInvestigational

  10. Drug

    BK-MDA

    go.drugbank.com/drugs/DB12809
    Investigational

    BK-MDA has been used in trials studying the treatment of Bladder Exstrophy and Urinary Incontinence.

    Synonyms: BK-MDA