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Displaying results 461 - 470 of 3599 in total
  1. Target

    Beta adrenergic receptor

    go.drugbank.com/bio_entities/BE0004872
    TargetHumans

    G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, activating bifurcated signaling pathways (PubMed:2831218, PubMed:7915137). … G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway (PubMed:10212248, PubMed:12391161, PubMed:15358775).

    Polypeptides: Beta-1 adrenergic receptor, Beta-2 adrenergic receptorFunction: alpha-2A adrenergic receptor binding, beta-adrenergic receptor activity
  2. Target

    Muscarinic acetylcholine receptor

    go.drugbank.com/bio_entities/BE0004890
    TargetHumans

    Muscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia (PubMed:24256733, PubMed:3443095, PubMed:36690613). … The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2Function: G protein-coupled acetylcholine receptor activity, G protein-coupled acetylcholine receptor activity
  3. Target

    Macrophage receptor MARCO

    go.drugbank.com/bio_entities/BE0009001
    TargetHumans

    Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508).

    Polypeptides: Macrophage receptor MARCOSynonyms: Scavenger receptor class A member 2, Macrophage receptor with collagenous structure
  4. Target

    Histamine H1 receptor

    go.drugbank.com/bio_entities/BE0009144
    CarrierTargetMouse

    In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well ...

    Polypeptides: Histamine H1 receptor
  5. Target

    Dopamine receptor D2

    go.drugbank.com/bio_entities/BE0009377
    TargetRat

    Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:1321233).

    Polypeptides: Dopamine receptor D2Synonyms: Dopamine D2 receptor, D(2) dopamine receptor
  6. Target

    Melanocortin receptor 3

    go.drugbank.com/bio_entities/BE0009683
    TargetHumans

    G protein-coupled receptor for melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8463333).

    Polypeptides: Melanocortin receptor 3Function: corticotropin receptor activity
  7. Target

    Asialoglycoprotein receptor 1

    go.drugbank.com/bio_entities/BE0010188
    TargetCarrierTransporterHumans

    Upon ligand binding, the receptor-ligand complex is internalized and trafficked to a sorting organelle, where dissociation occurs. The receptor is then recycled back to the cell surface

    Polypeptides: Asialoglycoprotein receptor 1Function: asialoglycoprotein receptor activity
  8. Target

    GABA(B) Receptor

    go.drugbank.com/bio_entities/BE0010194
    Target

    Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating … Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating

    Polypeptides: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2Synonyms: GABA-B receptor 1, GABA-B receptor 2
  9. Target

    Interleukin-21 receptor

    go.drugbank.com/bio_entities/BE0010657
    TargetHumans

    This is a receptor for interleukin-21

    Polypeptides: Interleukin-21 receptorSynonyms: IL-21 receptor, Novel interleukin receptor
  10. Target

    Neuromedin-B receptor

    go.drugbank.com/bio_entities/BE0013104
    TargetHumans

    Receptor for neuromedin-B (PubMed:1655761). … Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity)

    Polypeptides: Neuromedin-B receptorSynonyms: Neuromedin-B-preferring bombesin receptor