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Displaying results 4711 - 4720 of 10000 in total
  1. Target

    Microtubule-associated protein 2

    go.drugbank.com/bio_entities/BE0001100
    TargetHumans

    The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules

    Polypeptides: Microtubule-associated protein 2Synonyms: MAP-2
  2. Target

    2-oxo-tetronate isomerase

    go.drugbank.com/bio_entities/BE0001368
    TargetEscherichia coli (strain K12)

    Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo-tetronate.

    Polypeptides: 2-oxo-tetronate isomeraseSynonyms: 2-dehydrotetronate isomerase
  3. Target

    CDP-paratose 2-epimerase

    go.drugbank.com/bio_entities/BE0001635
    TargetSalmonella typhi

    Catalyzes the isomeration of CDP-paratose to CDP-tyvelose.

    Polypeptides: CDP-paratose 2-epimeraseSynonyms: CDP-tyvelose 2-epimerase
  4. Target

    (S)-2-haloacid dehalogenase

    go.drugbank.com/bio_entities/BE0001647
    TargetPseudomonas sp. (strain YL)

    Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 (PubMed:7490277, PubMed:9614112). … Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids (PubMed:7490277, PubMed:9614112).

    Polypeptides: (S)-2-haloacid dehalogenaseSynonyms: L-2-haloacid dehalogenase, 2-haloalkanoic acid dehalogenase
  5. Target

    Beta-lactamase SHV-2

    go.drugbank.com/bio_entities/BE0002029
    TargetEscherichia coli

    This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins.

    Polypeptides: Beta-lactamase SHV-2
  6. Target

    Acyl-CoA thioesterase 2

    go.drugbank.com/bio_entities/BE0002038
    TargetEscherichia coli (strain K12)

    Thioesterase that has relatively broad substrate specificity, hydrolyzing primarily medium- and long-chain acyl-CoA substrates to free fatty acids and CoA (PubMed:1645722, PubMed:20547355, PubMed:24271180). Functions in the thioesterase-...

    Polypeptides: Acyl-CoA thioesterase 2
  7. Target

    Inactive dihydropteroate synthase 2

    go.drugbank.com/bio_entities/BE0002087
    TargetMycobacterium leprae (strain TN)

    Has very low affinity for the DHPS substrate 6-hydroxymethyl-7,8-dihydropterin-pyrophosphate, but can bind the inhibitor dapsone. Seems to lack dihydropteroate synthase activity, and does probably not function in folate metabolism (By si...

    Polypeptides: Inactive dihydropteroate synthase 2Synonyms: DHPS 2, Dihydropteroate pyrophosphorylase 2
  8. Target

    Prolyl 3-hydroxylase 2

    go.drugbank.com/bio_entities/BE0002206
    TargetEnzymeHumans

    Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (PubMed:18487197). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens ...

    Polypeptides: Prolyl 3-hydroxylase 2
  9. Target

    Adenylosuccinate synthetase isozyme 2

    go.drugbank.com/bio_entities/BE0002228
    TargetHumans

    Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP

    Polypeptides: Adenylosuccinate synthetase isozyme 2Synonyms: AdSS 2, AMPSase 2
  10. Target

    Mitochondrial glutamate carrier 2

    go.drugbank.com/bio_entities/BE0002275
    TransporterHumans

    Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)

    Polypeptides: Mitochondrial glutamate carrier 2Synonyms: GC-2, Glutamate/H(+) symporter 2