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Displaying results 4721 - 4730 of 10000 in total

Drug
Nafamostat
go.drugbank.com/drugs/DB12598
Investigational
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. … The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing continuous renal replacement therapy due to acute kidney injury.
Synonyms: p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine
Drug
Octenidine
go.drugbank.com/drugs/DB12624
Investigational
Octenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, LösungCategories: Heterocyclic Compounds, 1-Ring
Drug
CC-115
go.drugbank.com/drugs/DB12740
Investigational
CC-115 has been used in trials studying the treatment of Prostate Cancer, Neoplasm Metastasis, Ewing's Osteosarcoma, Glioblastoma Multiforme, and Chronic Lymphocytic Leukemia, among others.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Lometrexol
go.drugbank.com/drugs/DB12769
Investigational
Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Pegvaliase
go.drugbank.com/drugs/DB12839
ApprovedInvestigational
Food and Drug Administration and European Medicines Agency approved pegvaliase-pqpz in May 2018 for the treatment of adult patients with phenylketonuria (PKU). … /L to 3690 µmol/L [A33286].
Drug
Reproterol
go.drugbank.com/drugs/DB12846
Investigational
Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
Synonyms: 7-(3-((2-(3,5-Dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)theophyllineCategories: Heterocyclic Compounds, 2-Ring, Selective Beta 2-adrenergic Agonists
Drug
Quizartinib
go.drugbank.com/drugs/DB12874
ApprovedInvestigational
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated … [A260651] Therefore, quizartinib is proven to be a beneficial addition to the current AML treatment regimen, although serious side effects such as QT prolongation necessitates further research to optimize
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)urea
Drug
RO-4987655
go.drugbank.com/drugs/DB12933
Investigational
RO4987655 has been used in trials studying the treatment of Neoplasms.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Pyronaridine
go.drugbank.com/drugs/DB12975
Investigational
Pyronaridine has been investigated for the treatment of Malaria.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Biapenem
go.drugbank.com/drugs/DB13028
Investigational
It is a carbapenem antibiotic with a methyl group on the 1-beta position, which gives it stability against degradation by dehydropeptidase I.[A275008]
Categories: Heterocyclic Compounds, 2-Ring