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Displaying results 4751 - 4760 of 10000 in total
  1. Target

    Interphotoreceptor matrix proteoglycan 2

    go.drugbank.com/bio_entities/BE0004942
    TargetHumans

    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin

    Polypeptides: Interphotoreceptor matrix proteoglycan 2
  2. Target

    Endonuclease 8-like 2

    go.drugbank.com/bio_entities/BE0005817
    TargetHumans

    Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.

    Polypeptides: Endonuclease 8-like 2Synonyms: Nei homolog 2, Nei-like protein 2
  3. Target

    Orexin receptor type 2

    go.drugbank.com/bio_entities/BE0005865
    TargetHumans

    G protein-coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin (PubMed:26950369, PubMed:33547286, PubMed:35614071, PubMed:9491897). Upon neuropeptide ligand bin...

    Polypeptides: Orexin receptor type 2Synonyms: Ox-2-R, Hypocretin receptor type 2
  4. Target

    Penicillin-binding protein 2

    go.drugbank.com/bio_entities/BE0008389
    TargetStaphylococcus aureus

    Polypeptides: Penicillin-binding protein 2
  5. Target

    Diacylglycerol O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0008719
    EnzymeTargetHumans

    Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides (PubMe...

    Polypeptides: Diacylglycerol O-acyltransferase 2Synonyms: Diglyceride acyltransferase 2
  6. Target

    Alpha-2-HS-glycoprotein

    go.drugbank.com/bio_entities/BE0009048
    TargetHumans

    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions

    Polypeptides: Alpha-2-HS-glycoproteinSynonyms: Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein
  7. Target

    LIM domain kinase 2

    go.drugbank.com/bio_entities/BE0009456
    TargetHumans

    Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, Pub...

    Polypeptides: LIM domain kinase 2Synonyms: LIMK-2
  8. Target

    Transmembrane protease serine 2

    go.drugbank.com/bio_entities/BE0009920
    TargetHumans

    Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption

    Polypeptides: Transmembrane protease serine 2
  9. Target

    Serum paraoxonase/arylesterase 2

    go.drugbank.com/bio_entities/BE0009921
    TargetHumans

    Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, a...

    Polypeptides: Serum paraoxonase/arylesterase 2Synonyms: PON 2, A-esterase 2
  10. Target

    Cancer/testis antigen 2

    go.drugbank.com/bio_entities/BE0010686
    TargetHumans

    Polypeptides: Cancer/testis antigen 2Synonyms: Autoimmunogenic cancer/testis antigen NY-ESO-2