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Displaying results 471 - 480 of 3482 in total
  1. Drug

    HSD-016

    go.drugbank.com/drugs/DB12419
    Investigational

    Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

  2. Drug

    Glasdegib

    go.drugbank.com/drugs/DB11978
    ApprovedInvestigational

    Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. … This analysis concluded that the presence of p-cyano ureas presented good physicochemical and pharmacokinetic properties from which glasdegib was developed.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  3. Drug

    Xylometazoline

    go.drugbank.com/drugs/DB06694
    Approved

    [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.

    Mixtures: XYLAZOL PEDİYATRİK 0,5 MG/ML + 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 10 ML, Otrivin Duo 0,5 mg/ml + 0,6 mg/ml Nasenspray, LösungProducts: NASENSPRAY SINE AL 1MG/ML, OTRIVINE CARE 1MG/ML DOZ AYARLI BURUN SPREYİ, 10 ML
  4. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains.

  5. Drug

    Carbocisteine

    go.drugbank.com/drugs/DB04339
    ApprovedInvestigational

    Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to t...

    Synonyms: L-carbocysteine, S-carboxymethyl-L-cysteineProducts: MUCOSIS 50 MG/ML ŞURUP, 100 ML, MUKO-S 250 MG/5 ML ŞURUP, 100 ML
  6. Drug

    Trilaciclib

    go.drugbank.com/drugs/DB15442
    ApprovedInvestigational

    Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    Carthamus tinctorius flower bud

    go.drugbank.com/drugs/DB14278
    Approved

    Carthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  8. Drug

    Zanthoxylum clava-herculis whole

    go.drugbank.com/drugs/DB14353
    Approved

    Zanthoxylum clava-herculis whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  9. Drug

    BMS-791826

    go.drugbank.com/drugs/DB15023
    Investigational

    BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).

  10. Drug

    Blinatumomab

    go.drugbank.com/drugs/DB09052
    ApprovedInvestigational

    [L46991,L46996] Blinatumomab has a short half-life, requiring patients to receive a continuous infusion over 4-week cycles using a portable mini-pump for optimum delivery.[A254826]