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Nicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalMost animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. … An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra.
Mixtures: Lebody Bu W Renewal Up, Niacinamide 250mg With 50mg CCategories: Alimentary Tract and MetabolismRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways … Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: RISPERDAL CONSTA 25MG, Nu-risperidoneNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalIt appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolProchlorperazine
go.drugbank.com/drugs/DB00433ApprovedInvestigationalVet approved[label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors. … [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in 1956.
Synonyms: Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine, N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazineProducts: Nu-prochlor Tab 10mg, Nu-prochlor Tab 5mgDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Categories: Alimentary Tract and MetabolismProducts: Nu-domperidone 10 Mg Tablets, MOTIDONE TABLET 10MGMagnesium oxide
go.drugbank.com/drugs/DB01377ApprovedInvestigationalIt is used as an antacid and mild laxative and has many nonmedicinal uses. … Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide.
Mixtures: Cyclo/Mag 10mg/200mg, Super Daily No 2Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnIt belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. … Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
Categories: Alimentary Tract and Metabolism, Genito Urinary System and Sex HormonesSynonyms: N-(4-chlorophenylsulfonyl)-N'-propylurea, N-(p-chlorobenzenesulfonyl)-N'-propylureaMiconazole
go.drugbank.com/drugs/DB01110ApprovedInvestigationalVet approved[A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream. … [A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams
Mixtures: Vobaderm 1mg/g + 20mg/g Creme, Up and Up Miconazole 1Categories: Imidazole and Triazole Derivatives, Vaginal Creams, Foams, and JelliesPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigational[F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma by the FDA on September 4, 2014,[L2954] becoming the first approved therapy against PD-1. … [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: KEYTRUDA SOLUTION FOR INFUSION 25MG/ML, Keytruda 100mg Solution for InfusionNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigational[A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins. … failure,[L7099] and chronic anal fissure.
Categories: Nitrates and Nitrites, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseSynonyms: NG