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Displaying results 4911 - 4920 of 10000 in total
  1. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.

  2. Drug

    Aceprometazine

    go.drugbank.com/drugs/DB01615
    Experimental

    Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine. … Aceprometazine is a is a drug with neuroleptic and anti-histamine properties.

  3. Drug

    Recombinant Bacterial ACE2 Receptors-like Enzyme

    go.drugbank.com/drugs/DB15741
    Investigational

    B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction. … B38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2

  4. Drug

    Sulfamoxole

    go.drugbank.com/drugs/DB08798
    Experimental

    Sulfamoxole is an antibacterial in the sulfonamide class.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide, 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide
  5. Drug

    Quavonlimab

    go.drugbank.com/drugs/DB16422
    Investigational

    Quavonlimab is under investigation in clinical trial NCT03179436 (Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)).

  6. Drug

    4-Hydroxytestosterone

    go.drugbank.com/drugs/DB01485
    IllicitInvestigational

    [A14385] Like formestane, 4-hydroxytesterone has been patented for use in decreasing estrogen production in the body, but no such indication currently exists. 4-Hydroxytestosterone was first patented in … It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by the World Anti-Doping Agency.

  7. Drug

    Pantethine

    go.drugbank.com/drugs/DB11190
    Approved

    It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. … Pantethine is available as a dietary supplement for lowering blood cholesterol and triglycerides.

    Synonyms: D-Bis(N-pantothenyl-beta-aminoethyl) disulfide
  8. Drug

    Allisartan isoproxil

    go.drugbank.com/drugs/DB18880
    Investigational

    Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).

    Categories: Agents Acting on the Renin-Angiotensin System, Angiotensin II receptor antagonists
  9. Drug

    Triflupromazine

    go.drugbank.com/drugs/DB00508
    ApprovedVet approved

    A phenothiazine used as an antipsychotic agent and as an antiemetic.

  10. Drug

    Zeranol

    go.drugbank.com/drugs/DB11478
    ExperimentalVet approved

    Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. … It is 3-4x more potent as an estrogen agonist than the related compound zearalenone.

    Categories: Estrogens, Non-Steroidal