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Displaying results 4941 - 4950 of 10000 in total
  1. Target

    Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

    go.drugbank.com/bio_entities/BE0010803
    TargetHumans

    Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating … Also, is able to hydrolyze the 5-phosphate of phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P3), 1D-myo-inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate (PubMed:10764818, PubMed:

    Polypeptides: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1Synonyms: SH2 domain-containing inositol 5'-phosphatase 1, SHIP-1
  2. Target

    1-phosphatidylinositol 3-phosphate 5-kinase

    go.drugbank.com/bio_entities/BE0021269
    TargetHumans

    Also catalyzes the phosphorylation of phosphatidylinositol on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:22621786). … Autophosphorylation inhibits its own phosphatidylinositol 3-phosphate 5-kinase activity, stimulates FIG4 lipid phosphatase activity and down-regulates lipid product formation (PubMed:33098764).

    Polypeptides: 1-phosphatidylinositol 3-phosphate 5-kinaseSynonyms: Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type III
  3. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Mixtures: LİDORİN %5+%5 KREM, 1 ADET 5 G, LIDOCAINA E PRILOCAINA TEVASynonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, alpha-n-Propylamino-2-methylpropionanilide
  4. Drug

    Ferric derisomaltose

    go.drugbank.com/drugs/DB15617
    ApprovedInvestigational

    [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells.

    Products: MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML, Diafer 50 mg/ml Injektionslösung
  5. Drug

    Valganciclovir

    go.drugbank.com/drugs/DB01610
    ApprovedInvestigational

    As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases. … Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections.

    Categories: Heterocyclic Compounds, 2-RingProducts: RUNAVIR®450 MG, VALGOVIR® 450 MG
  6. Drug

    Glucosamine

    go.drugbank.com/drugs/DB01296
    Approved

    Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance … [A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter.

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderSynonyms: 2-amino-2-deoxy-D-glucose, D-Glucosamine
  7. Drug

    Peginterferon beta-1a

    go.drugbank.com/drugs/DB09122
    ApprovedInvestigational

    [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing forms of MS. … Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body.

    Synonyms: PEG IFN-beta-1a, Peginterferon beta-1aMixtures: PLEGRİDY 63 MCG/0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML, PLEGRİDY 63 MCG/0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML
  8. Drug

    Risdiplam

    go.drugbank.com/drugs/DB15305
    ApprovedInvestigational

    [L15331,L15336] Set to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and relatively accessible treatment option for patients with SMA regardless … Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA).

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: Evrysdi Powder for oral solution 0.75 mg/mL, EVRYSDI POWDER FOR ORAL SOLUTION 0.75 MG/ML
  9. Target

    Pyrroline-5-carboxylate reductase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0000225
    TargetHumans

    Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:16730026, PubMed:19648921, PubMed:23024808

    Polypeptides: Pyrroline-5-carboxylate reductase 1, mitochondrialSynonyms: P5CR 1, P5C reductase 1
  10. Target

    Pregnancy-specific beta-1-glycoprotein 5

    go.drugbank.com/bio_entities/BE0008996
    TargetHumans

    Polypeptides: Pregnancy-specific beta-1-glycoprotein 5Synonyms: PSBG-5, PS-beta-G-5