Search
Corticotropin-releasing hormone receptor 2
go.drugbank.com/bio_entities/BE0014244TargetHumansG protein-coupled receptor for CRH, UCN, UCN2 and UCN3 stress hormones, which plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:22689579, PubMed:32004470, PubMed:36335102)....
Polypeptides: Corticotropin-releasing hormone receptor 2Synonyms: CRFR-2, CRF-R-22-hydroxyacylsphingosine 1-beta-galactosyltransferase
go.drugbank.com/bio_entities/BE0015078EnzymeHumansCatalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system (PubMed...
Polypeptides: 2-hydroxyacylsphingosine 1-beta-galactosyltransferaseFatty-acid amide hydrolase 2
go.drugbank.com/bio_entities/BE0015331EnzymeHumansCatalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to thei...
Polypeptides: Fatty-acid amide hydrolase 2Synonyms: Oleamide hydrolase 2, Anandamide amidohydrolase 2Sodium/myo-inositol cotransporter 2
go.drugbank.com/bio_entities/BE0017647TransporterHumansInvolved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1 (PubMed:15172003, PubMed:19032932).
Polypeptides: Sodium/myo-inositol cotransporter 2Synonyms: Na(+)/myo-inositol cotransporter 2, Sodium/myo-inositol transporter 2Mitochondrial amidoxime reducing component 2
go.drugbank.com/bio_entities/BE0017987EnzymeHumansCatalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:21029045, PubMed:24423752). As a component of prodrug-converting system, reduc...
Polypeptides: Mitochondrial amidoxime reducing component 2Synonyms: MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2Bcl-2-like protein 10
go.drugbank.com/bio_entities/BE0019838TargetHumansUnder apoptotic stress conditions, dissociates from ITPR1 and is displaced from mitochondria-associated endoplasmic reticulum membranes, leading to increased Ca(2+) transfer to mitochondria which promotes
Polypeptides: Bcl-2-like protein 10SUMO-activating enzyme subunit 2
go.drugbank.com/bio_entities/BE0020840TargetHumansThe heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine...
Polypeptides: SUMO-activating enzyme subunit 2Synonyms: Ubiquitin-like modifier-activating enzyme 2Deoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Mixtures: Debiline HSynonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acidVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigationalAntitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VINBLASTINA10 MG X 1 FCO., VINCABLAS® 10 MG/VIALStage II Follicular Lymphoma
go.drugbank.com/conditions/DBCOND0080969Drugs: ObinutuzumabSynonyms: Stage 2 Follicular Lymphoma ( FL)