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Displaying results 41 - 50 of 226 in total
  1. Pathway

    Zaleplon Action Pathway

    smpdb.ca/view/SMP0126830
    Drug action

    Functioning within the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex, it shares certain pharmacological attributes with benzodiazepines despite its distinct chemical structure.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Zaleplon · Calcium · Magnesium cation +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  2. Pathway

    Oxazepam Action Pathway

    smpdb.ca/view/SMP0126135
    Drug action

    Like other benzodiazepines, oxazepam exerts its anxiolytic effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA(A) receptors, the main inhibitory neurotransmitter receptors in the … They bind to the interface between alpha (α) and gamma (γ) subunits on the receptor, commonly referred to as the benzodiazepine binding site, and modulate the receptor such that its inhibitory response

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Oxazepam · Calcium · Magnesium cation +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  3. Pathway

    Thiocolchicoside Action Pathway (New)

    smpdb.ca/view/SMP0125071
    Drug action

    Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human cortex. GABAergic neurons are involved in myorelaxation, anxiolytic treatment, sedation, and anesthetics. … Thiocolchicoside has a selective and potent affinity for g-aminobutyric acid A (GABA-A) receptors and acts on muscular contractures by activating the GABA inhibitory pathways thereby behaving as a potent

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  4. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    Its actions are mediated by enhancement of gamma-aminobutyric acid activity.

  5. Pathway

    Ketazolam Action Pathway

    smpdb.ca/view/SMP0126132
    Drug action

    As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. … Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA), which results in sedative, hypnotic, anxiolytic, anticonvulsant, muscle relaxant and amnesic action.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Ketazolam +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  6. Pathway

    Estazolam Action Pathway

    smpdb.ca/view/SMP0126125
    Drug action

    As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects GABA by increasing GABA affinity for the GABA receptor.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Estazolam · Calcium · Magnesium cation +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  7. Pathway

    Quazepam Action Pathway

    smpdb.ca/view/SMP0126138
    Drug action

    Like other benzodiazepines, quazepam likely exerts its effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA(A) receptors, the main inhibitory neurotransmitter receptors in the mammalian … They bind to the interface between alpha (α) and gamma (γ) subunits on the receptor, commonly referred to as the benzodiazepine binding site, and modulate the receptor such that its inhibitory response

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Quazepam +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  8. Pathway

    Flunitrazepam Action Pathway

    smpdb.ca/view/SMP0126128
    Drug action

    As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Flunitrazepam +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  9. Pathway

    Remimazolam Action Pathway

    smpdb.ca/view/SMP0126145
    Drug action

    Like other benzodiazepines, remimazolam exerts its therapeutic effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA(A) receptors, the main inhibitory neurotransmitter receptors … They bind to the interface between alpha (α) and gamma (γ) subunits on the receptor, commonly referred to as the benzodiazepine binding site, and modulate the receptor such that its inhibitory response

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2
  10. Pathway

    Phenobarbital Action Pathway

    smpdb.ca/view/SMP0126831
    Drug action

    Functioning as a nonselective depressant of the central nervous system, it engages inhibitory gamma-aminobutyric acid subtype receptors, thereby modulating chloride currents across receptor channels and … Phenobarbital is absorbed to varying degrees through oral, rectal, or parenteral routes, with the salts exhibiting quicker absorption compared to the acids.

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Phenobarbital · Calcium · Magnesium cation +3 more
    Enzymes: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid type B receptor subunit 2