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Wilson's Disease
go.drugbank.com/conditions/DBCOND0032702Synonyms: Iron &/or copper &/or magnesium disorder (& [haemochromatosis] or [Wilson's disease])Fostemsavir Action Pathway
smpdb.ca/view/SMP0125963Drug actionThe inability for the virus to attach and release viral components into the host cell greatly reduces the replication of the virus.
Fc Epsilon Receptor I Signaling in Mast Cells
smpdb.ca/view/SMP0000358Signaling-4, and interleukin-5). … Activated mast cells also synthesize and secrete lipid-derived mediators (such as prostaglandins, leukotrienes, and platelet-activating factor) and cytokines (notably tumor necrosis factor-alpha, interleukin
Atorvastatin Action Pathway
smpdb.ca/view/SMP0000131Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Atorvastatin Action Pathway (New)
smpdb.ca/view/SMP0124555Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.
Trisalicylate-Choline Action Pathway
smpdb.ca/view/SMP0000703Drug actionTrisalicylate-Choline (also named Choline Magnesium Trisalicylate) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat pain and fever. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Choline magnesium trisalicylate +5 moreInsulin Signalling
smpdb.ca/view/SMP0000391SignalingGlycogen and lipid biosynthesis are upregulated, and conversely, glycogen and fatty acid metabolism are down-regulated. Insulin also modulates transcription and translation. … It stimulates the storage of energy and inhibits the breakdown of high energy metabolites.
Ras Signaling Pathway
smpdb.ca/view/SMP0063784SignalingRAS proteins are GTP-binding proteins and must be bound to GTP to be active. Active RAS binds and activates effector enzymes that control cell proliferation, survival and other cell behaviours. … PI3K is also involved in the regulation of the actin cytoskeleton and transcription factor pathways.
Insulin (New)
smpdb.ca/view/SMP0127691PhysiologicalInsulin is synthesized as preproinsulin and processed to proinsulin. Proinsulin is then converted to insulin and C-peptide and stored in secretary granules awaiting release on demand. … Insulin promotes glycogen synthesis, lipid synthesis, protein synthesis, DNA synthesis, and cellular growth and differentiation.
Lovastatin Action Pathway (New)
smpdb.ca/view/SMP0124570Drug actionStatins are a class of medications that lower lipid levels and are administered to reduce illness and mortality in people who are at high risk of cardiovascular disease. … LDL-R localizes to the endoplasmic reticulum for transport and exocytosis to the cell surface.